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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
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Not CommonRésumée par IA
Litsea cubeba
Litsea cubeba
Médecine traditionnelle chinoise pour les troubles digestifs et cardiaques
PubMed · Litsea cubeba essential oil: Extraction, chemical composition, antioxidant and antimicrobial properties, and applications in the food industry. (2024)
PubMed · Ethnopharmacological Properties and Medicinal Uses of <i>Litsea cubeba</i>. (2019)
Révisé par : HerbAlly Editorial Team, Medical herbalists and healthcare professionals
Dernière mise à jour : April 2026
Calculer une dose sûre de Litsea cubeba
Calculateur gratuit de posologie — doses adultes et enfants selon le poids.
The primary active compounds in Litsea cubeba, specifically citral (geranial and neral), are responsible for its biological effects. Citral exhibits antimicrobial and anti-inflammatory properties by disrupting bacterial cell membranes and modulating inflammatory pathways. The presence of limonene and linalool contributes to the herb's calming and analgesic effects, often utilized in aromatherapy. Evidence Level: C.
Does Litsea cubeba interact with any medications?
There is limited clinical data regarding specific drug interactions for Litsea cubeba (Evidence Level: C). However, due to its citral content, there is a theoretical risk of interaction with drugs metabolized by liver enzymes, though this is more common with internal use of the essential oil. Patients taking anticoagulants or sedatives should exercise caution and consult a healthcare provider before use, as additive effects may occur.
What is the recommended dosage for Litsea cubeba?
For topical application, the essential oil should be diluted to a concentration of 1-2% in a carrier oil to minimize skin irritation. For internal use as a tea, a typical traditional dosage involves steeping approximately 5 grams of the dried fruit per cup of boiling water. Due to the potency of the essential oil, internal medicinal use should be supervised by a qualified practitioner.
Is Litsea cubeba safe to use during pregnancy?
Litsea cubeba is generally considered unsafe during pregnancy, particularly in therapeutic doses. The high citral content may stimulate uterine contractions or affect fetal development. While small amounts in food are likely harmless, medicinal use of the essential oil or concentrated extracts should be avoided by pregnant and breastfeeding women. Always consult a doctor before using herbal supplements during pregnancy.
What are the benefits of Litsea cubeba essential oil?
Litsea cubeba essential oil is primarily used for its antimicrobial, anti-inflammatory, and calming properties. Traditionally used in Chinese medicine for digestive issues, the oil is now popular in aromatherapy for stress relief and skin care applications. Research (Evidence Level: C) suggests it may help inhibit bacterial growth and reduce inflammation, making it useful for minor skin infections or muscle pain when applied topically.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Litsea cubeba is an aromatic woody plant used traditionally in medicine and as a spice, known for its essential oil with antioxidant, antimicrobial, and analgesic properties [PMID:31159425, 38731572, 39013008].
Contexte
Litsea cubeba (Lour.) Pers., also known as May Chang tree or Chinese pepper, is a woody oil plant predominant in tropical and subtropical regions of India, China, Taiwan, and Japan [PMID:31159425, 39525418]. It is utilized as an industrial crop for the production of fragrant essential oils, primarily from its fruits and peels [PMID:31615834, 34203392].
Usages traditionnels
It has been traditionally used to treat gastro-intestinal ailments such as diarrhea, stomachache, indigestion, and gastroenteritis, as well as diabetes, edema, cold, arthritis, asthma, and traumatic injury [PMID:31159425]. It is also widely used as a traditional Chinese medicine and spice [PMID:30654451].
Composés actifs
The essential oil is dominated by monoterpenes, specifically trans-citral and cis-citral, along with d-limonene [PMID:35793977, 39525418]. Other identified constituents include lignans (including 7',9-epoxylignans and dibenzylbutyrolactone lignans) [PMID:30654451], sesquineolignans [PMID:34688469], aromatic glycosides [PMID:28541690], N-alkylamides (such as cubebamide) [PMID:37328937], benzylisoquinoline alkaloids [PMID:28152615], flavonoids, phenolics, organic acids, and antioxidant peptides [PMID:39500772, 38398540, 40428488].
Mécanisme d'action
The essential oil exhibits antimicrobial activity by potentially penetrating and destroying the inner and outer membranes of bacteria like E. coli [PMID:25372706] and inhibiting C. albicans via binding to secretory aspartate protease (SAP5) and β-1,3-glucan synthase (β-1,3-GS) [PMID:35793977]. Certain N-alkylamides may prevent inflammatory diseases by binding to the 5-LOX enzyme [PMID:37328937], while antioxidant peptides may ameliorate oxidative stress via the Nrf2/Keap1 pathway [PMID:40428488].
Preuves cliniques
Preuve APain/Nociception
L. cubeba demonstrated peripheral antinociceptive properties (inhibiting acetic-acid-induced writhing) and central analgesic effects at the spinal level (increasing heat-stimulated-nocifensive response latencies in tail flick assays) in animal models [PMID:38731572].
Preuve DInflammation
Isolated N-alkylamides and sesquineolignans showed inhibitory effects against NO production in RAW264.7 macrophages [PMID:37328937, 34688469].
Preuve DOxidative Stress
Methanol extracts and fractions showed remarkable antioxidant activity compared to alpha-tocopherol and ascorbic acid [PMID:16239077].
Sécurité et effets indésirables
The essential oil is reported to exert acute and genetic toxicity as well as cytotoxicity [PMID:31159425].
Synthèse des preuves
Evidence is primarily based on in vitro studies, animal models, and literature reviews. A systematic review confirms analgesic potential in animal models, but there are no human clinical trials provided.
Sources PubMed
1.PMID: 39500772 (2024) — Aromatic plants as cosmeceuticals: benefits and applications for skin health. · Planta
2.PMID: 31159425 (2019) — Ethnopharmacological Properties and Medicinal Uses of Litsea cubeba. · Plants (Basel, Switzerland)
3.PMID: 30654451 (2019) — Lignans from the Twigs of Litsea cubeba and Their Bioactivities. · Molecules (Basel, Switzerland)
5.PMID: 39013008 (2024) — Litsea cubeba essential oil: Extraction, chemical composition, antioxidant and antimicrobial properties, and applications in the food industry. · Journal of food science
6.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
9.PMID: 34203392 (2021) — An Overview on Total Valorization of Litsea cubeba as a New Woody Oil Plant Resource toward a Zero-Waste Biorefinery. · Molecules (Basel, Switzerland)
11.PMID: 38068969 (2023) — The Association between BZIP Transcription Factors and Flower Development in Litsea cubeba. · International journal of molecular sciences
12.PMID: 35793977 (2022) — Litsea cubeba Essential Oil: Component Analysis, Anti-Candida albicans Activity and Mechanism Based on Molecular Docking. · Journal of oleo science
13.PMID: 36848837 (2023) — Preparation and application of cinnamon-Litsea cubeba compound essential oil microcapsules for peanut kernel postharvest storage. · Food chemistry
14.PMID: 33366967 (2020) — The complete chloroplast genome sequence of Litsea cubeba. · Mitochondrial DNA. Part B, Resources
15.PMID: 37960137 (2023) — Main Habitat Factors Driving the Phenotypic Diversity of Litsea cubeba in China. · Plants (Basel, Switzerland)
16.PMID: 37328937 (2024) — N-alkylamides from Litsea cubeba (Lour.) Pers. with potential anti-inflammatory activity. · Natural product research
17.PMID: 36941959 (2023) — Dietary Litsea cubeba essential oil supplementation improves growth performance and intestinal health of weaned piglets. · Animal nutrition (Zhongguo xu mu shou yi xue hui)
18.PMID: 25372706 (2014) — Antibacterial activity and kinetics of Litsea cubeba oil on Escherichia coli. · PloS one
19.PMID: 34688469 (2021) — Bioactive sesquineolignans from the twigs of Litsea cubeba. · Chinese journal of natural medicines
20.PMID: 40428488 (2025) — Antioxidant Peptides from the Fruit Source of the Oil Crop Litsea cubeba Ameliorate FFA-Induced Oxidative Stress Injury: Based on Nrf2/Keap1 Pathway and Molecular Dynamics Simulations. · Foods (Basel, Switzerland)
21.PMID: 33984740 (2021) — Effects of different frying temperatures on the aroma profiles of fried mountain pepper (Litsea cubeba (Lour.) Pers.) oils and characterization of their key odorants. · Food chemistry
22.PMID: 28152615 (2017) — A new N-methoxyl-carbonyl benzylisoquinoline from Litsea cubeba. · Journal of Asian natural products research
23.PMID: 38397578 (2024) — Effects of Litsea cubeba Essential Oil-Chitosan/Corn Starch Composite Films on the Quality and Shelf-Life of Strawberry (Fragaria × ananassa). · Foods (Basel, Switzerland)
24.PMID: 39525418 (2022) — Antimicrobial activity of essential oils extracted from Litsea cubeba. · Forestry research
25.PMID: 38398540 (2024) — Non-Volatile Component and Antioxidant Activity: A Comparative Analysis between Litsea cubeba Branches and Leaves. · Molecules (Basel, Switzerland)
26.PMID: 39517151 (2024) — Effect of Litsea cubeba and Cinnamon Essential Oil Nanoemulsion Coatings on the Preservation of Plant-Based Meat Analogs. · Foods (Basel, Switzerland)
27.PMID: 38288379 (2023) — Exploring possible benefits of Litsea cubeba Pers. extract on growth, meat quality, and gut flora in white-feather broilers. · Frontiers in veterinary science
28.PMID: 39526280 (2023) — Overexpression of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enhances the monoterpene content in Litsea cubeba. · Forestry research
29.PMID: 28541690 (2017) — Bioactive Glycosides from the Twigs of Litsea cubeba. · Journal of natural products