Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Sesquiterpenoid compound 5 from root bark exhibited potent anti-neuroinflammatory effects in LPS-induced BV-2 cells, exceeding the effectiveness of curcumin [PMID:40090561]
Kukoamine A from root bark ameliorated age-related decrease in swimming activity and preserved muscle mitochondrial morphology in C. elegans [PMID:40850658]
Lignanamides and glycosides from root bark exhibited potent antihyperlipidemic activities in HepG2 cells, reducing intracellular triglyceride and total cholesterol levels [PMID:29737867, 28890177]
A formula containing L. chinense (Osteo-F) improved arthritis scores, bone mineral content, and cartilage integrity in rat models [PMID:40357339]
Water extract of L. chinense roots increased secretion of pro-inflammatory cytokines (TNF-α, IL-6) and enhanced phagocytic activity of macrophages [PMID:32215941]
Synthèse des preuves
Sources PubMed
- 1.PMID: 32533890 (2020) — Fruit ripening in Lycium barbarum and Lycium ruthenicum is associated with distinct gene expression patterns. · FEBS open bio
- 2.PMID: 40090561 (2025) — Sesquiterpenoids isolated from the root bark of Lycium chinense. · Phytochemistry
- 3.PMID: 40850658 (2026) — Kukoamine A from the root bark of Lycium chinense Miller enhances mobility in an aged Caenorhabditis elegans model by regulating mitochondrial function through HSF-1-mediated upregulation of heat shock proteins. · Journal of ethnopharmacology
- 4.PMID: 36912477 (2023) — A comprehensive review on the ethnobotany, phytochemistry, pharmacology and quality control of the genus Lycium in China. · Food & function
- 5.PMID: 40357339 (2025)