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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Macadamia integrifolia
Australian native nut tree used by Aboriginal Australians as nutritive food medicine; oil rich in palmitoleic acid with skin healing properties.
Macadamia nut oil, derived from the Australian native Macadamia integrifolia, is a nutrient-dense oil traditionally used as a food medicine by Aboriginal Australians and now valued for its skin-healing and moisturizing properties. Its high content of palmitoleic acid, along with oleic acid, linoleic acid, phytosterols, and squalene, contributes to its anti-inflammatory, antioxidant, and emollient effects. This monograph summarizes its evidence-based topical and dietary uses, safety profile, and pharmacological mechanisms.
The primary active compound, palmitoleic acid (a monounsaturated omega-7 fatty acid), exerts anti-inflammatory effects by activating peroxisome proliferator-activated receptor alpha (PPAR-α) and reducing pro-inflammatory cytokines such as IL-6 and TNF-α. Oleic acid enhances skin barrier function by modulating lipid synthesis and promoting ceramide production, while linoleic acid supports epidermal integrity via conversion to arachidonic acid and subsequent eicosanoid signaling. Phytosterols and squalene provide antioxidant protection by scavenging free radicals and inhibiting lipid peroxidation, thereby reducing oxidative stress in cutaneous tissues.
Australian native nut tree used by Aboriginal Australians as nutritive food medicine; oil rich in palmitoleic acid with skin healing properties.
Macadamia nut oil, derived from the Australian native Macadamia integrifolia, is a nutrient-dense oil traditionally used as a food medicine by Aboriginal Australians and now valued for its skin-healing and moisturizing properties. Its high content of palmitoleic acid, along with oleic acid, linoleic acid, phytosterols, and squalene, contributes to its anti-inflammatory, antioxidant, and emollient effects. This monograph summarizes its evidence-based topical and dietary uses, safety profile, and pharmacological mechanisms.
The primary active compound, palmitoleic acid (a monounsaturated omega-7 fatty acid), exerts anti-inflammatory effects by activating peroxisome proliferator-activated receptor alpha (PPAR-α) and reducing pro-inflammatory cytokines such as IL-6 and TNF-α. Oleic acid enhances skin barrier function by modulating lipid synthesis and promoting ceramide production, while linoleic acid supports epidermal integrity via conversion to arachidonic acid and subsequent eicosanoid signaling. Phytosterols and squalene provide antioxidant protection by scavenging free radicals and inhibiting lipid peroxidation, thereby reducing oxidative stress in cutaneous tissues.