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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Garcinia mangostana
The pericarp (rind) of the mangosteen fruit contains xanthones, particularly alpha-mangostin, which have remarkable antioxidant activity; used in Southeast Asian medicine for infections and inflammation.
Mangosteen pericarp (Garcinia mangostana) is a tropical fruit rind rich in xanthones, particularly alpha-mangostin, which exhibit potent antioxidant, anti-inflammatory, and antimicrobial activities. Traditionally used in Southeast Asian medicine for skin infections, diarrhea, and wound healing, modern research supports its potential in managing oxidative stress, inflammation, and certain infections, though clinical evidence remains limited.
Alpha-mangostin and other xanthones inhibit cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), reducing prostaglandin and leukotriene synthesis. They also suppress nuclear factor-kappa B (NF-κB) activation, decreasing pro-inflammatory cytokines (TNF-α, IL-6). Additionally, xanthones scavenge reactive oxygen species (ROS) and upregulate antioxidant enzymes (SOD, catalase). Antimicrobial effects involve disruption of bacterial cell membranes and inhibition of biofilm formation. Anti-tumor activity is mediated through induction of apoptosis via caspase activation and cell cycle arrest at G1 phase.
The pericarp (rind) of the mangosteen fruit contains xanthones, particularly alpha-mangostin, which have remarkable antioxidant activity; used in Southeast Asian medicine for infections and inflammation.
Mangosteen pericarp (Garcinia mangostana) is a tropical fruit rind rich in xanthones, particularly alpha-mangostin, which exhibit potent antioxidant, anti-inflammatory, and antimicrobial activities. Traditionally used in Southeast Asian medicine for skin infections, diarrhea, and wound healing, modern research supports its potential in managing oxidative stress, inflammation, and certain infections, though clinical evidence remains limited.
Alpha-mangostin and other xanthones inhibit cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), reducing prostaglandin and leukotriene synthesis. They also suppress nuclear factor-kappa B (NF-κB) activation, decreasing pro-inflammatory cytokines (TNF-α, IL-6). Additionally, xanthones scavenge reactive oxygen species (ROS) and upregulate antioxidant enzymes (SOD, catalase). Antimicrobial effects involve disruption of bacterial cell membranes and inhibition of biofilm formation. Anti-tumor activity is mediated through induction of apoptosis via caspase activation and cell cycle arrest at G1 phase.