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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 25 articles PubMed · modèle : gemma4:31b
Résumé
Menyanthes trifoliata (buckbean) is a medicinal aquatic plant found in Asia, Europe, and North America with documented anti-inflammatory, antioxidant, and cytotoxic properties [PMID:30610508, 31737178].
Contexte
Menyanthes trifoliata, also known as buckbean or bogbean, is an emergent aquatic plant that grows on peat bogs and swamps in Europe, North America, and Asia [PMID:31737178, 35050061].
Usages traditionnels
It has been used in traditional medicine for centuries as a remedy for anemia, lack of appetite [PMID:30610508], and in Swedish traditional medicine for the treatment of inflammatory kidney diseases such as glomerulonephritis [PMID:23196151]. In China, it is used as a hypnotic remedy in ethnomedicines [PMID:39647592].
Composés actifs
The plant contains lupane triterpenoids (including 23-O-trans-feruloylcylicodiscic acid) [PMID:29658298], polyphenolic compounds such as sinapinic, ferulic, syringic, and vanilic acids [PMID:30610508], and secoiridoids including dihydrofoliamenthin, menthiafolin, and loganin [PMID:17262264]. It also contains immunomodulating polysaccharide fractions [PMID:15813366] and iridoids [PMID:19615800].
Mécanisme d'action
The herb may exert anti-inflammatory effects through the inhibition of platelet activating factor (PAF)-induced exocytosis and the inhibition of elastase activity [PMID:23195814, 23196151]. Certain extracts demonstrate the ability to induce apoptosis in grade IV glioma cells [PMID:30610508] and influence the expression of antioxidant (e.g., HO-1, NRF2) and inflammation-related genes (e.g., IL-6, TNF-α) [PMID:31737178].
Preuves cliniques
Preuve DInflammation/Edema
Rhizome decoction inhibited carrageenan-induced rat paw edema and ethyl phenylpropiolate-induced rat ear edema in a dose-dependent manner [PMID:23196151].
Preuve DAcute Renal Failure
Oral administration of water decoction from rhizomes preserved renal function (higher GFR) after renal ischemia in rats [PMID:23195814].
Preuve DCancer (Glioma)
Root extracts exhibited cytotoxic effects and induced apoptosis in grade IV glioma cells in vitro, without affecting normal human astrocytes [PMID:30610508].
Preuve DInsomnia
Evaluated as a sedative-hypnotic candidate in mice using EEG/EMG and behavioral tests [PMID:39647592].
Sécurité et effets indésirables
In a metallomic profiling study, compendial permissible limits for elements were not exceeded, and no evidence of non-carcinogenic risk was found [PMID:36266322]. A rhizome decoction showed only minor hemolytic activity [PMID:23196151].
Interactions médicamenteuses
Bogbean is listed as a herbal product that may potentially increase the risk of bleeding or potentiate the effects of warfarin therapy [PMID:10902065].
Synthèse des preuves
The current evidence is primarily based on in vitro studies and animal models (Level D), demonstrating potential anti-inflammatory, anti-cancer, and sedative activities; there are no human clinical trials provided in the source material.
Sources PubMed
1.PMID: 29658298 (2019) — Anti-inflammatory lupane triterpenoids from Menyanthes trifoliata. · Journal of Asian natural products research
2.PMID: 10902065 (2000) — Potential interactions between alternative therapies and warfarin. · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
3.PMID: 35050061 (2022) — Diurnal Change of the Photosynthetic Light-Response Curve of Buckbean (Menyanthes trifoliata), an Emergent Aquatic Plant. · Plants (Basel, Switzerland)
4.PMID: 36751911 (2023) — Plant phenology and species-specific traits control plant CH4 emissions in a northern boreal fen. · The New phytologist
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— Antioxidant Activity and Profile of Phenolic Compounds in Selected Herbal Plants.
· Plant foods for human nutrition (Dordrecht, Netherlands)
6.PMID: 30610508 (2019) — Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells. · Cytotechnology
7.PMID: 15813366 (2004) — Immunomodulating polysaccharide fractions of Menyanthes trifoliata L. · Zeitschrift fur Naturforschung. C, Journal of biosciences
8.PMID: 36833486 (2023) — The Influence of Shallow Peatland Water Quality on Characteristics of the Occurrence of Selected Herb Species in the Peatlands of Eastern Poland. · International journal of environmental research and public health
9.PMID: 39647592 (2025) — Evaluation of the sedative-hypnotic effects of Menyanthes trifoliata L. extract in mice. · Journal of ethnopharmacology
10.PMID: 36266322 (2022) — Novel metallomic profiling and non-carcinogenic risk assessment of botanical ingredients for use in herbal, phytopharmaceutical and dietary products using HR-ICP-SFMS. · Scientific reports
11.PMID: 31737178 (2019) — An Evaluation of the DNA-Protective Effects of Extracts from Menyanthes trifoliata L. Plants Derived from In Vitro Culture Associated with Redox Balance and Other Biological Activities. · Oxidative medicine and cellular longevity
12.PMID: 23195814 (1994) — The effect of Menyanthes trifoliata L. on acute renal failure might be due to PAF-inhibition. · Phytomedicine : international journal of phytotherapy and phytopharmacology
13.PMID: 21622434 (2010) — Development and multiplexing of microsatellite markers in the polyploid perennial herb, Menyanthes trifoliata (Menyanthaceae). · American journal of botany
14.PMID: 23196151 (1995) — Anti-inflammatory studies on Menyanthes trifoliata related to the effect shown against renal failure in rats. · Phytomedicine : international journal of phytotherapy and phytopharmacology
15.PMID: 19615800 (2009) — Effect of the temperature and the exclusion of UVB radiation on the phenolics and iridoids in Menyanthes trifoliata L. leaves in the subarctic. · Environmental pollution (Barking, Essex : 1987)
16.PMID: 12230887 (2002) — Selective cytotoxicity evaluation in anticancer drug screening of fractionated plant extracts. · Journal of biomolecular screening
17.PMID: 17262264 (1989) — [Further investigations regarding distribution and structure of the bitter principles from Menyanthes trifoliata]. · Planta medica
18.PMID: 33373786 (2021) — Process-based modeling to assess the nutrient removal efficiency of two endangered hydrophytes: Linking nutrient-cycle with a multiple-quotas approach. · The Science of the total environment
19.PMID: 41300392 (2025) — Vegetation and Landscape Shift After Beaver Settlement in a Mountainous Area. · Biology
20.PMID: 40885875 (2025) — Integrated profiling of essential metals, phenolic compounds, anti-inflammatory and hydroxyl radical scavenging activities for five medicinal plants. · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
21.PMID: 33385841 (2021) — Biogeochemistry of macrophytes, sediments and porewaters in thermokarst lakes of permafrost peatlands, western Siberia. · The Science of the total environment
22.PMID: 19889484 (2010) — The distribution of (137)Cs, K, Rb and Cs in plants in a Sphagnum-dominated peatland in eastern central Sweden. · Journal of environmental radioactivity