Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Liriodenine showed strong inhibition of human breast and lung cancer cells [PMID:21941890]. Micheliolide (MCL) inhibited viability, migration, and invasion of human glioma U251MG cells [PMID:32863900] and exerted selective cytotoxic effects on CD34+CD38- leukemic stem cells [PMID:27542251].
Ethanolic extract of flower buds exhibited significant antihyperglycemic and antidiabetic activity in glucose-overloaded and alloxan-induced diabetic rat models [PMID:21279181].
Ethanol extract of leaves (EEMC) demonstrated antidepressant activity in forced swim and tail suspension tests, and anxiolytic activity in elevated plus maze and light/dark tests in mice [PMID:36052952].
Micheliolide treatment alleviated pancreatic injury (necrosis, edema, vacuolation) and reduced serum amylase and lipase levels in murine models via Nrf2 activation [PMID:39467351].
Methanol extracts of leaves, seeds, stem, and root barks exhibited broad-spectrum antibacterial activity; liriodenine was identified as an active constituent of the root bark [PMID:12490248].
Grossesse et allaitement
Synthèse des preuves
Sources PubMed
- 1.PMID: 38692344 (2024) — Phenylethanoid glycosides from Michelia champaca leaves. · Phytochemistry
- 2.PMID: 38471573 (2024) — Flavonoid glycosides from the leaves of Michelia champaca. · Fitoterapia
- 3.PMID: 12490248 (2002) — Antimicrobial activity of Michelia champaca. · Fitoterapia
- 4.PMID: 33457969 (2020) — Complete chloroplast genome sequence of Michelia champaca var. champaca Linnaeus, an ornamental tree species of Magnoliaceae. · Mitochondrial DNA. Part B, Resources
- 5.PMID: 38454977 (2023) — Antioxidant and antiaging activities of Cinnamomum burmannii, Michelia champaca and their combinations. · Narra J