Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Millettia pinnata
Indian coastal legume tree used in Ayurveda for skin diseases and whose seed oil has diverse medical applications.
Millettia pinnata (syn. Pongamia pinnata) is a coastal legume tree used in Ayurveda for skin diseases and rheumatism. Its seed oil contains bioactive compounds such as pongamol, karanjin, and fatty acids, which exhibit antifungal, anti-inflammatory, and wound-healing properties. Limited clinical evidence supports its topical use for dermatological conditions, but internal use of the seed oil is contraindicated due to toxicity.
Karanjin and pongamol inhibit fungal cell wall synthesis and modulate inflammatory pathways by suppressing COX-2 and NF-κB activation. Tannins contribute to wound healing through astringent and antimicrobial effects, while fatty acids in the seed oil enhance skin barrier repair. The anti-inflammatory action involves downregulation of TNF-α and IL-6, and analgesic effects may be mediated via opioid and vanilloid receptor pathways.
Indian coastal legume tree used in Ayurveda for skin diseases and whose seed oil has diverse medical applications.
Millettia pinnata (syn. Pongamia pinnata) is a coastal legume tree used in Ayurveda for skin diseases and rheumatism. Its seed oil contains bioactive compounds such as pongamol, karanjin, and fatty acids, which exhibit antifungal, anti-inflammatory, and wound-healing properties. Limited clinical evidence supports its topical use for dermatological conditions, but internal use of the seed oil is contraindicated due to toxicity.
Karanjin and pongamol inhibit fungal cell wall synthesis and modulate inflammatory pathways by suppressing COX-2 and NF-κB activation. Tannins contribute to wound healing through astringent and antimicrobial effects, while fatty acids in the seed oil enhance skin barrier repair. The anti-inflammatory action involves downregulation of TNF-α and IL-6, and analgesic effects may be mediated via opioid and vanilloid receptor pathways.