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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Mitragyna inermis
West African tree in same genus as kratom; bark used for malaria and fever management.
Mitragyna inermis is a West African tree in the same genus as kratom, traditionally used for malaria, fever, edema, and jaundice. Modern uses include anti-malarial, antipyretic, and diuretic applications, supported by limited clinical evidence (Level C). Key active compounds include mitraphylline, rhynchophylline, alkaloids, tannins, and flavonoids, which contribute to its pharmacological effects.
The antimalarial activity of Mitragyna inermis is thought to involve inhibition of heme polymerization and modulation of immune responses, similar to other quinoline-based antimalarials. Mitraphylline and rhynchophylline exhibit anti-inflammatory and antipyretic effects through COX-2 inhibition and suppression of pro-inflammatory cytokines such as TNF-α and IL-6. The diuretic action may be mediated by increased renal blood flow and inhibition of sodium reabsorption in the distal tubules. Flavonoids and tannins provide additional antioxidant and hepatoprotective properties.
West African tree in same genus as kratom; bark used for malaria and fever management.
Mitragyna inermis is a West African tree in the same genus as kratom, traditionally used for malaria, fever, edema, and jaundice. Modern uses include anti-malarial, antipyretic, and diuretic applications, supported by limited clinical evidence (Level C). Key active compounds include mitraphylline, rhynchophylline, alkaloids, tannins, and flavonoids, which contribute to its pharmacological effects.
The antimalarial activity of Mitragyna inermis is thought to involve inhibition of heme polymerization and modulation of immune responses, similar to other quinoline-based antimalarials. Mitraphylline and rhynchophylline exhibit anti-inflammatory and antipyretic effects through COX-2 inhibition and suppression of pro-inflammatory cytokines such as TNF-α and IL-6. The diuretic action may be mediated by increased renal blood flow and inhibition of sodium reabsorption in the distal tubules. Flavonoids and tannins provide additional antioxidant and hepatoprotective properties.