Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Mullein works through two primary mechanisms: demulcent and expectorant actions. The leaves and flowers contain significant amounts of mucilage, a gelatinous substance that coats and soothes irritated mucous membranes in the throat. This creates a protective barrier that reduces the urge to cough. Additionally, mullein contains saponins, which are believed to help thin mucus secretions, making them easier to expel from the respiratory tract. This combination effectively relieves dry, hacking coughs (Evidence level: B/Traditional).
Does mullein interact with any medications?
Currently, there are no well-documented clinical drug interactions associated with mullein leaf or flower preparations. Because mullein is not systemically absorbed in significant amounts when used as a tea or ear oil, it generally does not interfere with pharmaceutical metabolism. However, because it can alter mucus consistency, patients taking prescription expectorants or respiratory medications should consult a healthcare provider before adding mullein to their regimen to avoid overlapping effects (Evidence level: Traditional).
What is the recommended dosage for mullein tea?
The standard adult dosage for mullein tea is 1 to 2 grams of dried leaf or flower steeped in hot water, taken 3 to 4 times daily. To prepare, pour boiling water over the herb and steep for 10 to 15 minutes. It is crucial to strain the tea through a fine mesh, cheesecloth, or coffee filter to remove the tiny, irritating plant hairs before drinking to prevent throat irritation (Evidence level: Traditional).
Is mullein safe to use during pregnancy and breastfeeding?
Mullein is generally considered safe for use during pregnancy and breastfeeding when consumed in recommended amounts. Herbal authorities classify it as a gentle herb with a long history of use without reported toxicity to the mother or fetus. However, as with any herbal supplement, clinical data specific to pregnancy is limited. Pregnant women should consult a qualified healthcare provider or midwife before use to ensure it is appropriate for their specific health circumstances (Evidence level: Traditional).
Can mullein ear oil be used for ear infections?
Yes, mullein flower oil is a traditional remedy for earaches and mild ear infections. The oil is often combined with garlic for added antimicrobial benefits. The standard application involves placing 2 to 3 drops of warmed oil into the affected ear twice daily. However, this treatment is strictly contraindicated if the eardrum is perforated or if there is fluid drainage from the ear; in these cases, a physician should be consulted immediately (Evidence level: B).
What are the side effects of taking mullein?
Mullein is well-tolerated by most individuals, but side effects can occur. The most common issue is irritation caused by the plant's fine hairs, which can lead to contact dermatitis or throat irritation if not properly filtered from teas. Rare side effects include mild gastrointestinal upset or allergic reactions. To avoid respiratory irritation, ensure that any loose leaf tea is strained through a fine filter to remove the microscopic hairs before consumption (Evidence level: Traditional).
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Common mullein (Verbascum thapsus L.) is a medicinal plant used traditionally for pulmonary, inflammatory, and wound-related conditions [PMID:16222647, PMID:35088467].
Contexte
Verbascum thapsus L., also known as great mullein or common mullein, is a biennial plant indigenous to Europe, northern Africa, and western and central Asia, and has been introduced to the Americas and Australia [PMID:35088467, PMID:37009556].
Usages traditionnels
It has been used to treat pulmonary problems, inflammatory diseases, asthma, spasmodic coughs, diarrhoea, migraine headaches [PMID:16222647], lung, skin, and throat disorders [PMID:35088467], and as an antispasmodic, anti-tubercular agent, and wormicide in tribal medicine [PMID:22463730]. Root extracts have been used for toothache, stiffness, and seizures [PMID:35088467], while other traditional uses include treating genitourinary infections [PMID:26239850] and whooping cough [PMID:39183880].
Composés actifs
Phytoconstituents include flavonoids, saponins, tannins, terpenoids, glycosides (iridoid, phenylethanoid, and phenylpropanoid), coumarin, hesperidin, and vitamin C [PMID:35088467, PMID:22463730]. Specific identified compounds include p-coumaric acid, ferulic acid, rutin [PMID:36297503], and acteoside [PMID:40549319].
Mécanisme d'action
Traditional uses may rely on the anti-inflammatory action of phytochemicals such as quercetin [PMID:34356473]. In vitro studies suggest the plant may induce apoptosis in Trichomonas vaginalis [PMID:26239850] and exhibit antioxidant activity via DPPH and ABTS radical scavenging [PMID:38279434, PMID:31456524].
Preuves cliniques
Preuve BEpisiotomy wound healing
A randomized, double-blind, controlled clinical trial evaluated the effect of Verbascum Thapsus on episiotomy wound healing in primiparous women [PMID:34103042].
Sécurité et effets indésirables
Toxicity to brine shrimp and radish seed germination was observed at higher concentrations of extracts [PMID:12241986].
Synthèse des preuves
The evidence consists primarily of in vitro studies, animal/plant bioassays, and reviews of traditional use, with one randomized controlled trial regarding wound healing. Overall clinical evidence in humans is limited.
Sources PubMed
1.PMID: 16222647 (2005) — Common mullein (Verbascum thapsus L.): recent advances in research. · Phytotherapy research : PTR
2.PMID: 35088467 (2022) — Health-promoting and disease-mitigating potential of Verbascum thapsus L. (common mullein): A review. · Phytotherapy research : PTR
3.PMID: 22463730 (2012) — Anthelmintic and relaxant activities of Verbascum Thapsus Mullein. · BMC complementary and alternative medicine
4.PMID: 36297503 (2022) — Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells. · Pharmaceutics
5.PMID: 31456524 (2020) — The Antioxidant, Anticarcinogenic and Antimicrobial Properties of Verbascum thapsus L.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
· Medicinal chemistry (Shariqah (United Arab Emirates))
6.PMID: 12241986 (2002) — Biological activity of common mullein, a medicinal plant. · Journal of ethnopharmacology
7.PMID: 36082042 (2022) — The complete chloroplast genome of Verbascum thapsus L. (Scrophulariaceae) and its phylogenetic affinities. · Mitochondrial DNA. Part B, Resources
8.PMID: 37009556 (2023) — The Complete Genome Sequence of Verbascum thapsus (Scrophulariaceae, Lamiales), the Common Mullein. · Biodiversity genomes
9.PMID: 34356473 (2021) — Searching for Scientific Explanations for the Uses of Spanish Folk Medicine: A Review on the Case of Mullein (Verbascum, Scrophulariaceae). · Biology
10.PMID: 26239850 (2015) — Effect of Verbascum thapsus ethanol extract on induction of apoptosis in Trichomonas vaginalis in vitro. · Infectious disorders drug targets
11.PMID: 38279434 (2023) — Antioxidant, AChE inhibitory, and anticancer effects of Verbascum thapsus extract. · Cellular and molecular biology (Noisy-le-Grand, France)
12.PMID: 34103042 (2021) — The effect of the Verbascum Thapsus on episiotomy wound healing in nulliparous women: a randomized controlled trial. · BMC complementary medicine and therapies
13.PMID: 39183880 (2024) — Bioassay-guided fractionation of Verbascum thapsus extract and its combination with polyvinyl alcohol in the form electrospun nanofibrous membrane for efficient wound dressing application. · Heliyon
14.PMID: 40549319 (2025) — Acteoside as a multifunctional natural glycoside: therapeutic potential across various diseases. · Inflammopharmacology