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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Nandina domestica
Japanese garden shrub used in Kampo medicine for respiratory conditions and fruit antitussive properties.
Nandina domestica (Heavenly Bamboo) is a Japanese garden shrub used in Kampo medicine primarily for its antitussive and respiratory-supporting properties. Its fruit contains alkaloids such as nantenine, berberine, and domesticine, which contribute to its antimicrobial, anti-inflammatory, and mild sedative effects. Despite traditional use, evidence is limited (Level C), and safety concerns arise from alkaloid toxicity, especially in pregnancy and children.
Nantenine, a major alkaloid, exhibits antitussive activity by modulating central cough centers and possibly antagonizing serotonin (5-HT2) receptors, reducing cough reflex sensitivity. Berberine exerts antimicrobial effects through bacterial membrane disruption and inhibition of DNA gyrase, while also suppressing inflammation via NF-κB pathway inhibition and reduction of pro-inflammatory cytokines. Domesticine may contribute to mild sedation through interaction with GABAergic or dopaminergic systems, though precise mechanisms remain under investigation.
Japanese garden shrub used in Kampo medicine for respiratory conditions and fruit antitussive properties.
Nandina domestica (Heavenly Bamboo) is a Japanese garden shrub used in Kampo medicine primarily for its antitussive and respiratory-supporting properties. Its fruit contains alkaloids such as nantenine, berberine, and domesticine, which contribute to its antimicrobial, anti-inflammatory, and mild sedative effects. Despite traditional use, evidence is limited (Level C), and safety concerns arise from alkaloid toxicity, especially in pregnancy and children.
Nantenine, a major alkaloid, exhibits antitussive activity by modulating central cough centers and possibly antagonizing serotonin (5-HT2) receptors, reducing cough reflex sensitivity. Berberine exerts antimicrobial effects through bacterial membrane disruption and inhibition of DNA gyrase, while also suppressing inflammation via NF-κB pathway inhibition and reduction of pro-inflammatory cytokines. Domesticine may contribute to mild sedation through interaction with GABAergic or dopaminergic systems, though precise mechanisms remain under investigation.