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Panax vietnamensis
The most valuable Vietnamese medicinal herb, grown only in the Ngoc Linh mountains, with highest ginsenoside content.
Panax vietnamensis, known as Vietnamese ginseng or Nhan Sam, is a rare and highly valued adaptogenic herb endemic to the Ngoc Linh mountains, distinguished by its exceptionally high ginsenoside content. It is traditionally used to combat fatigue, support immune function, and enhance cognitive performance, with modern research focusing on its adaptogenic, immunomodulatory, and nootropic properties. Key active compounds include ginsenoside MR2, majonoside R2, ginsenoside Rb1, and Rg1, which contribute to its diverse pharmacological effects.
The adaptogenic and anti-stress effects of Panax vietnamensis are primarily mediated by its unique ginsenosides, particularly majonoside R2 and ginsenoside MR2, which modulate the hypothalamic-pituitary-adrenal (HPA) axis and reduce cortisol levels. These compounds also enhance immune function by stimulating natural killer (NK) cell activity and macrophage phagocytosis, while their nootropic actions involve upregulation of brain-derived neurotrophic factor (BDNF) and modulation of cholinergic and dopaminergic pathways. Additionally, ginsenoside Rb1 and Rg1 exhibit antioxidant and anti-inflammatory properties through activation of Nrf2 and inhibition of NF-κB signaling.
The most valuable Vietnamese medicinal herb, grown only in the Ngoc Linh mountains, with highest ginsenoside content.
Panax vietnamensis, known as Vietnamese ginseng or Nhan Sam, is a rare and highly valued adaptogenic herb endemic to the Ngoc Linh mountains, distinguished by its exceptionally high ginsenoside content. It is traditionally used to combat fatigue, support immune function, and enhance cognitive performance, with modern research focusing on its adaptogenic, immunomodulatory, and nootropic properties. Key active compounds include ginsenoside MR2, majonoside R2, ginsenoside Rb1, and Rg1, which contribute to its diverse pharmacological effects.
The adaptogenic and anti-stress effects of Panax vietnamensis are primarily mediated by its unique ginsenosides, particularly majonoside R2 and ginsenoside MR2, which modulate the hypothalamic-pituitary-adrenal (HPA) axis and reduce cortisol levels. These compounds also enhance immune function by stimulating natural killer (NK) cell activity and macrophage phagocytosis, while their nootropic actions involve upregulation of brain-derived neurotrophic factor (BDNF) and modulation of cholinergic and dopaminergic pathways. Additionally, ginsenoside Rb1 and Rg1 exhibit antioxidant and anti-inflammatory properties through activation of Nrf2 and inhibition of NF-κB signaling.