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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Nopal (Opuntia ficus-indica) is a cactus known for its nutritional value and bioactive compounds that exhibit antioxidant, anti-inflammatory, and metabolic benefits [PMID:35921318, PMID:25232708].
Contexte
Opuntia ficus-indica, commonly known as nopal or prickly pear, is a dicotyledonous angiosperm of the Cactaceae family [PMID:25232708, PMID:36771630]. It is highly adapted to arid and semi-arid climates in tropical and subtropical regions and is cultivated globally, particularly in Mexico, Africa, the Middle East, and India [PMID:25232708, PMID:35927821, PMID:37631119].
Usages traditionnels
Nopal has been used in traditional medicine for conditions including diabetes, acne, arthrosis, dermatosis, diarrhea, fever, high blood pressure, prostatitis, rheumatism, stomachache, tumors, warts, allergies, wounds, and colitis [PMID:35927821]. It is also traditionally used for its medicinal properties in Mexico [PMID:37233362].
Composés actifs
Bioactive components include betalains (such as betanin), polyphenols, flavonoids, tannins, phenolic acids, carotenoids, ascorbate, biopeptides, soluble and insoluble fibers, vitamins, polyunsaturated fatty acids, and amino acids [PMID:35921318, PMID:37631119, PMID:25232708, PMID:35927821, PMID:37860248].
Mécanisme d'action
Nopal may influence glucose metabolism by improving insulin sensitivity, reducing insulin resistance, and modulating gut microbiota [PMID:37994760]. Its beneficial effects are associated with the attenuation of oxidative stress and inflammation markers [PMID:38732528, PMID:37371904].
Preuves cliniques
Preuve BIrritable Bowel Syndrome (IBS)
Nopal fiber powder (10, 20, or 30 g/day) improved symptoms in the short term compared to placebo [PMID:32935904].
Preuve CHyperglycemia/Diabetes
Consumption of prickly pear cladodes is reported to exert hypoglycemic effects [PMID:35208623]; it is the most commonly used herbal hypoglycemic among persons of Mexican descent [PMID:11926665].
Preuve CObesity and Metabolic Syndrome
Preclinical studies show a significant capacity to prevent obesity and related co-morbidities, though clinical studies have shown mixed results [PMID:38732528].
Preuve DHepatic Steatosis
In obese Zucker rats, a diet containing 4% nopal reduced hepatic triglycerides by approximately 50% and reduced biomarkers of hepatocyte injury [PMID:23014486].
Sécurité et effets indésirables
Embedded prickly pear spines (glochids) can cause local and systemic inflammatory conditions, allergic contact dermatitis, and ocular keratoconjunctivitis [PMID:41941578, PMID:24669148]. The plant also has high potential as an invasive species [PMID:37631119].
Synthèse des preuves
Evidence is primarily based on reviews and preclinical animal models (Level C and D), with one randomized controlled trial (Level B) supporting its use for IBS symptoms.
Sources PubMed
1.PMID: 35921318 (2023) — Betalains: colours for human health. · Natural product research
2.PMID: 37631119 (2023) — Adapting to Climate Change with Opuntia. · Plants (Basel, Switzerland)
3.PMID: 36771630 (2023) — Opuntia ficus-indica Fruit: A Systematic Review of Its Phytochemicals and Pharmacological Activities. · Plants (Basel, Switzerland)
4.PMID: 24669148 (2014) — Prickly pear spine keratoconjunctivitis. · Middle East African journal of ophthalmology
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
PMID: 36501373 (2022) — Challenges Inherent in Controlling Prickly Pear Species; a Global Review of the Properties of Opuntia stricta, Opuntia ficus-indica and Opuntia monacantha. · Plants (Basel, Switzerland)
7.PMID: 25232708 (2014) — Nopal cactus (Opuntia ficus-indica) as a source of bioactive compounds for nutrition, health and disease. · Molecules (Basel, Switzerland)
8.PMID: 33670110 (2021) — Opuntia ficus-indica (L.) Mill.: A Multi-Benefit Potential to Be Exploited. · Molecules (Basel, Switzerland)
9.PMID: 35927821 (2022) — Opuntia ficus indica (L.) Mill. An Ancient Plant Source of Nutraceuticals. · Current topics in medicinal chemistry
10.PMID: 37371904 (2023) — Beneficial Effects of Opuntia spp. on Liver Health. · Antioxidants (Basel, Switzerland)
11.PMID: 37860248 (2023) — Opuntia ficus-indica (L.) Mill. - anticancer properties and phytochemicals: current trends and future perspectives. · Frontiers in plant science
12.PMID: 11926665 (2002) — Natural products used for diabetes. · Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
13.PMID: 37233362 (2023) — Decellularized Scaffolds of Nopal (Opuntia Ficus-indica) for Bioengineering in Regenerative Dentistry. · Journal of functional biomaterials
14.PMID: 31604414 (2019) — Nopal (Opuntia spp.) and its Effects on Metabolic Syndrome: New Insights for the Use of a Millenary Plant. · Current pharmaceutical design
15.PMID: 30456012 (2018) — Prickly pear cactus cladodes powder of Opuntia ficus indica as a cost effective biosorbent for dyes removal from aqueous solutions. · 3 Biotech
16.PMID: 26476894 (2016) — Application of Opuntia ficus-indica in bioremediation of wastewaters. A critical review. · Journal of environmental management
17.PMID: 39684127 (2024) — Extraction of Purple Prickly Pear (Opuntia ficus-indica) Mucilage by Microfiltration, Composition, and Physicochemical Characteristics. · Polymers
18.PMID: 34443606 (2021) — Prickly Pear Seed Oil Extraction, Chemical Characterization and Potential Health Benefits. · Molecules (Basel, Switzerland)
19.PMID: 38732528 (2024) — Usefulness of Opuntia spp. on the Management of Obesity and Its Metabolic Co-Morbidities. · Nutrients
20.PMID: 32935904 (2021) — Nopal fiber (Opuntia ficus-indica) improves symptoms in irritable bowel syndrome in the short term: a randomized controlled trial. · Neurogastroenterology and motility
21.PMID: 35208623 (2022) — Prickly Pear Cacti (Opuntia spp.) Cladodes as a Functional Ingredient for Hyperglycemia Management: A Brief Narrative Review. · Medicina (Kaunas, Lithuania)
22.PMID: 28805459 (2018) — Opuntia ficus-indica (L.) Miller as a source of bioactivity compounds for health and nutrition. · Natural product research
23.PMID: 37256773 (2023) — Developmental dynamics of crassulacean acid metabolism (CAM) in Opuntia ficus-indica. · Annals of botany
24.PMID: 25356040 (2014) — Review of natural products with hepatoprotective effects. · World journal of gastroenterology
25.PMID: 36233157 (2022) — Protective Effect of Nopal Cactus (Opuntia ficus-indica) Seed Oil against Short-Term Lipopolysaccharides-Induced Inflammation and Peroxisomal Functions Dysregulation in Mouse Brain and Liver. · International journal of molecular sciences
26.PMID: 39286769 (2024) — Phytochemical, biological, and nutritional properties of the prickly pear, Opuntia dillenii: A review. · Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
27.PMID: 37994760 (2023) — Unraveling the Role of Prickly Pear Extract as a Potent Nutraceutical Agent Against Metabolic Syndromes. · La Clinica terapeutica
29.PMID: 37050137 (2023) — Physicochemical, Nutritional, and Medicinal Properties of Opuntia ficus-indica (L.) Mill. and Its Main Agro-Industrial Use: A Review. · Plants (Basel, Switzerland)
30.PMID: 23014486 (2012) — Opuntia ficus indica (nopal) attenuates hepatic steatosis and oxidative stress in obese Zucker (fa/fa) rats. · The Journal of nutrition