Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Oxytropis kansuensis
Tibetan plateau herb used in Tibetan medicine (Sowa Rigpa) for liver and inflammatory conditions.
Oxytropis kansuensis is a Tibetan plateau herb used in Sowa Rigpa (Tibetan medicine) primarily for liver and inflammatory conditions. Its key active compounds include the toxic alkaloid swainsonine, along with flavonoids and tannins that contribute to its anti-inflammatory and hepatoprotective effects. Due to the presence of swainsonine, the herb requires careful dosing and supervision.
The anti-inflammatory effects are attributed to flavonoids and tannins that inhibit pro-inflammatory cytokines (e.g., TNF-α, IL-6) and modulate NF-κB signaling. Hepatoprotective actions involve upregulation of antioxidant enzymes (SOD, GPx) and reduction of lipid peroxidation, likely mediated by flavonoid compounds. Swainsonine, a potent α-mannosidase inhibitor, disrupts glycoprotein processing and can induce lysosomal storage disease at high doses, limiting its therapeutic window. Alkaloids may also contribute to antimicrobial activity through membrane disruption.
Tibetan plateau herb used in Tibetan medicine (Sowa Rigpa) for liver and inflammatory conditions.
Oxytropis kansuensis is a Tibetan plateau herb used in Sowa Rigpa (Tibetan medicine) primarily for liver and inflammatory conditions. Its key active compounds include the toxic alkaloid swainsonine, along with flavonoids and tannins that contribute to its anti-inflammatory and hepatoprotective effects. Due to the presence of swainsonine, the herb requires careful dosing and supervision.
The anti-inflammatory effects are attributed to flavonoids and tannins that inhibit pro-inflammatory cytokines (e.g., TNF-α, IL-6) and modulate NF-κB signaling. Hepatoprotective actions involve upregulation of antioxidant enzymes (SOD, GPx) and reduction of lipid peroxidation, likely mediated by flavonoid compounds. Swainsonine, a potent α-mannosidase inhibitor, disrupts glycoprotein processing and can induce lysosomal storage disease at high doses, limiting its therapeutic window. Alkaloids may also contribute to antimicrobial activity through membrane disruption.