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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Peperomia pellucida
Philippine and pantropical herb used officially for arthritis, gout, and skin conditions; approved by Philippine Department of Health.
Pansit-Pansitan (Peperomia pellucida) is a pantropical herb officially recognized by the Philippine Department of Health for its anti-inflammatory, analgesic, and uricosuric properties, traditionally used to manage arthritis, gout, and various skin conditions. Its key active compounds—pellucidine, flavonoids, apiol, dillapiole, and beta-sitosterol—contribute to its therapeutic effects through multiple pharmacological pathways. Despite limited clinical evidence (Grade C), it remains a widely used herbal remedy in Southeast Asia.
The anti-inflammatory and analgesic actions of Peperomia pellucida are primarily mediated by flavonoids and pellucidine, which inhibit cyclooxygenase (COX-1/COX-2) and lipoxygenase (5-LOX) enzymes, thereby reducing prostaglandin and leukotriene synthesis. Its uricosuric effect is attributed to apiol and dillapiole, which may inhibit renal urate reabsorption via modulation of URAT1 transporters, similar to other phthalide compounds. Additionally, beta-sitosterol and flavonoids provide antioxidant protection by scavenging reactive oxygen species and upregulating endogenous antioxidant enzymes such as superoxide dismutase and catalase.
Philippine and pantropical herb used officially for arthritis, gout, and skin conditions; approved by Philippine Department of Health.
Pansit-Pansitan (Peperomia pellucida) is a pantropical herb officially recognized by the Philippine Department of Health for its anti-inflammatory, analgesic, and uricosuric properties, traditionally used to manage arthritis, gout, and various skin conditions. Its key active compounds—pellucidine, flavonoids, apiol, dillapiole, and beta-sitosterol—contribute to its therapeutic effects through multiple pharmacological pathways. Despite limited clinical evidence (Grade C), it remains a widely used herbal remedy in Southeast Asia.
The anti-inflammatory and analgesic actions of Peperomia pellucida are primarily mediated by flavonoids and pellucidine, which inhibit cyclooxygenase (COX-1/COX-2) and lipoxygenase (5-LOX) enzymes, thereby reducing prostaglandin and leukotriene synthesis. Its uricosuric effect is attributed to apiol and dillapiole, which may inhibit renal urate reabsorption via modulation of URAT1 transporters, similar to other phthalide compounds. Additionally, beta-sitosterol and flavonoids provide antioxidant protection by scavenging reactive oxygen species and upregulating endogenous antioxidant enzymes such as superoxide dismutase and catalase.