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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Handroanthus impetiginosus
Large tree of South American rainforest; inner bark used by numerous Indigenous Amazonian peoples for cancer, infections and inflammation.
Pau d'Arco (Handroanthus impetiginosus) is a large South American tree whose inner bark has been used traditionally by Amazonian indigenous peoples for infections, cancer, and immune support. Its primary active compounds, lapachol and beta-lapachone, have demonstrated antimicrobial, antitumor, and immunomodulatory properties in preclinical studies, though clinical evidence remains limited (Level C).
Lapachol and beta-lapachone inhibit topoisomerase I and II, leading to DNA damage and apoptosis in cancer cells. They also generate reactive oxygen species (ROS) and interfere with mitochondrial function. Antimicrobial effects involve disruption of bacterial cell walls and fungal ergosterol synthesis. Immunomodulation occurs via upregulation of cytokines such as IL-2 and TNF-α, enhancing natural killer cell activity.
Large tree of South American rainforest; inner bark used by numerous Indigenous Amazonian peoples for cancer, infections and inflammation.
Pau d'Arco (Handroanthus impetiginosus) is a large South American tree whose inner bark has been used traditionally by Amazonian indigenous peoples for infections, cancer, and immune support. Its primary active compounds, lapachol and beta-lapachone, have demonstrated antimicrobial, antitumor, and immunomodulatory properties in preclinical studies, though clinical evidence remains limited (Level C).
Lapachol and beta-lapachone inhibit topoisomerase I and II, leading to DNA damage and apoptosis in cancer cells. They also generate reactive oxygen species (ROS) and interfere with mitochondrial function. Antimicrobial effects involve disruption of bacterial cell walls and fungal ergosterol synthesis. Immunomodulation occurs via upregulation of cytokines such as IL-2 and TNF-α, enhancing natural killer cell activity.