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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Pausinystalia johimbe
Central African tree bark containing yohimbine; alpha-2 adrenergic antagonist used for sexual dysfunction.
Pausinystalia johimbe is a Central African tree bark containing the indole alkaloid yohimbine, a selective alpha-2 adrenergic receptor antagonist. It is primarily used for erectile dysfunction and as an aphrodisiac, with additional traditional applications for weight loss and orthostatic hypotension. Key active compounds include yohimbine, alpha-yohimbine, beta-yohimbine, corynanthine, and alloyohimbine.
Yohimbine acts as a competitive antagonist at presynaptic alpha-2 adrenergic receptors, increasing norepinephrine release and sympathetic outflow. This leads to enhanced vasodilation in penile tissues via nitric oxide pathways, improved blood flow, and increased sexual arousal. Additionally, alpha-2 blockade may reduce appetite and stimulate lipolysis, contributing to weight loss effects. The compound also exhibits mild MAO-inhibitory properties at high doses, potentially influencing mood.
Central African tree bark containing yohimbine; alpha-2 adrenergic antagonist used for sexual dysfunction.
Pausinystalia johimbe is a Central African tree bark containing the indole alkaloid yohimbine, a selective alpha-2 adrenergic receptor antagonist. It is primarily used for erectile dysfunction and as an aphrodisiac, with additional traditional applications for weight loss and orthostatic hypotension. Key active compounds include yohimbine, alpha-yohimbine, beta-yohimbine, corynanthine, and alloyohimbine.
Yohimbine acts as a competitive antagonist at presynaptic alpha-2 adrenergic receptors, increasing norepinephrine release and sympathetic outflow. This leads to enhanced vasodilation in penile tissues via nitric oxide pathways, improved blood flow, and increased sexual arousal. Additionally, alpha-2 blockade may reduce appetite and stimulate lipolysis, contributing to weight loss effects. The compound also exhibits mild MAO-inhibitory properties at high doses, potentially influencing mood.