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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Petasites japonicus
Japanese edible plant with large leaves; young stalks eaten as vegetable; traditional use for cough and pain.
Petasites japonicus (fuki) is a traditional Japanese vegetable and medicinal herb used for cough, pain, and digestive support. Its primary active compounds include petasin and furanopetasin, which exhibit antispasmodic and anti-inflammatory effects, but the presence of hepatotoxic pyrrolizidine alkaloids necessitates careful processing for safe medicinal use.
Petasin and furanopetasin inhibit calcium influx in smooth muscle cells, producing antispasmodic effects on bronchial and gastrointestinal tissues. Flavonoids contribute additional anti-inflammatory activity via COX-2 inhibition. Pyrrolizidine alkaloids are metabolized by hepatic CYP450 enzymes to toxic pyrroles, which can cause veno-occlusive disease; therefore, only PA-free extracts are recommended for therapeutic applications.
Japanese edible plant with large leaves; young stalks eaten as vegetable; traditional use for cough and pain.
Petasites japonicus (fuki) is a traditional Japanese vegetable and medicinal herb used for cough, pain, and digestive support. Its primary active compounds include petasin and furanopetasin, which exhibit antispasmodic and anti-inflammatory effects, but the presence of hepatotoxic pyrrolizidine alkaloids necessitates careful processing for safe medicinal use.
Petasin and furanopetasin inhibit calcium influx in smooth muscle cells, producing antispasmodic effects on bronchial and gastrointestinal tissues. Flavonoids contribute additional anti-inflammatory activity via COX-2 inhibition. Pyrrolizidine alkaloids are metabolized by hepatic CYP450 enzymes to toxic pyrroles, which can cause veno-occlusive disease; therefore, only PA-free extracts are recommended for therapeutic applications.