Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Rheum tanguticum
Root of Tibetan rhubarb used in TCM and Tibetan medicine as a powerful purgative, liver herb, and blood-moving agent.
Rheum tanguticum (Tibetan rhubarb) is a potent purgative herb used in Traditional Chinese Medicine and Tibetan medicine for its laxative, hepatoprotective, and blood-moving properties. Its primary active compounds include anthraquinones such as emodin, rhein, aloe-emodin, chrysophanol, and physcion, which contribute to its laxative and anti-inflammatory effects. Despite its traditional use, clinical evidence is limited, and caution is warranted due to potential toxicity and drug interactions.
The laxative effect of Rheum tanguticum is primarily mediated by anthraquinone glycosides (e.g., sennosides) that are hydrolyzed in the colon to active aglycones, stimulating colonic peristalsis via inhibition of Na+/K+-ATPase and increasing water and electrolyte secretion. Rhein and emodin also inhibit pro-inflammatory cytokines (e.g., TNF-α, IL-6) and modulate NF-κB and MAPK pathways, contributing to anti-inflammatory and anticancer activities. Additionally, emodin has been shown to induce apoptosis in cancer cells through caspase activation and reactive oxygen species generation.
Root of Tibetan rhubarb used in TCM and Tibetan medicine as a powerful purgative, liver herb, and blood-moving agent.
Rheum tanguticum (Tibetan rhubarb) is a potent purgative herb used in Traditional Chinese Medicine and Tibetan medicine for its laxative, hepatoprotective, and blood-moving properties. Its primary active compounds include anthraquinones such as emodin, rhein, aloe-emodin, chrysophanol, and physcion, which contribute to its laxative and anti-inflammatory effects. Despite its traditional use, clinical evidence is limited, and caution is warranted due to potential toxicity and drug interactions.
The laxative effect of Rheum tanguticum is primarily mediated by anthraquinone glycosides (e.g., sennosides) that are hydrolyzed in the colon to active aglycones, stimulating colonic peristalsis via inhibition of Na+/K+-ATPase and increasing water and electrolyte secretion. Rhein and emodin also inhibit pro-inflammatory cytokines (e.g., TNF-α, IL-6) and modulate NF-κB and MAPK pathways, contributing to anti-inflammatory and anticancer activities. Additionally, emodin has been shown to induce apoptosis in cancer cells through caspase activation and reactive oxygen species generation.