Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Ricinus communis
Tropical shrub whose seeds yield castor oil (laxative) and deadly ricin toxin; wide traditional use.
Ricinus communis (castor bean) is a tropical shrub whose seeds yield castor oil, widely used as a stimulant laxative, and the potent toxin ricin. Its primary active compound is ricinoleic acid, which exerts laxative effects via EP3 prostanoid receptors. Despite traditional uses, evidence is limited (Level C) and safety concerns are significant due to ricin toxicity.
Ricinoleic acid, the primary fatty acid in castor oil, activates EP3 prostanoid receptors in the intestinal smooth muscle, leading to increased motility and secretion, thereby producing a laxative effect. Ricin, a ribosome-inactivating protein, inhibits protein synthesis by depurinating 28S rRNA, causing cell death and severe toxicity if seeds are ingested. Ricinine may contribute to central nervous system effects, while other fatty acids provide emollient properties for topical use.
Tropical shrub whose seeds yield castor oil (laxative) and deadly ricin toxin; wide traditional use.
Ricinus communis (castor bean) is a tropical shrub whose seeds yield castor oil, widely used as a stimulant laxative, and the potent toxin ricin. Its primary active compound is ricinoleic acid, which exerts laxative effects via EP3 prostanoid receptors. Despite traditional uses, evidence is limited (Level C) and safety concerns are significant due to ricin toxicity.
Ricinoleic acid, the primary fatty acid in castor oil, activates EP3 prostanoid receptors in the intestinal smooth muscle, leading to increased motility and secretion, thereby producing a laxative effect. Ricin, a ribosome-inactivating protein, inhibits protein synthesis by depurinating 28S rRNA, causing cell death and severe toxicity if seeds are ingested. Ricinine may contribute to central nervous system effects, while other fatty acids provide emollient properties for topical use.