Rosa roxburghii (Rosa roxburghii): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Rosa roxburghii provide antioxidant benefits?

Rosa roxburghii exerts antioxidant effects primarily through its exceptionally high ascorbic acid (vitamin C) content and natural superoxide dismutase (SOD) enzymes. These compounds work synergistically to neutralize free radicals and reduce oxidative stress at the cellular level. The hips also contain flavonoids including quercetin and anthocyanins, which provide additional antioxidant capacity by scavenging reactive oxygen species. This combination makes Rosa roxburghii one of the most antioxidant-dense medicinal fruits available (Evidence Level C, Traditional use).

Does Rosa roxburghii interact with any medications?

No significant drug interactions have been documented for Rosa roxburghii. However, due to its high vitamin C content, individuals taking anticoagulants like warfarin should maintain consistent intake, as vitamin C fluctuations may affect anticoagulant activity. The vitamin C in Rosa roxburghii can enhance iron absorption, which may be relevant for those on iron therapy or with iron-related conditions. Consult a healthcare provider when combining with prescription medications (Evidence Level C).

What is the recommended dosage for Rosa roxburghii?

The standard adult dosage for Rosa roxburghii is 5-10 grams of dried hips prepared as a tea or decoction, taken once to three times daily. To prepare, steep the dried hips in hot water for 10-15 minutes. Fresh hips may also be consumed directly as a food source. Dosage may vary based on individual needs, preparation method, and intended use. Traditional Chinese Medicine practitioners may adjust dosing based on specific digestive complaints (Evidence Level C, Traditional use).

Is Rosa roxburghii safe during pregnancy and breastfeeding?

Rosa roxburghii is generally considered safe during pregnancy and breastfeeding when consumed in normal food amounts. The hips have a long history of safe use as a food source in East Asian cultures and provide beneficial nutrients including vitamin C. However, pregnant and breastfeeding women should avoid excessive doses and consult their healthcare provider before using concentrated extracts or therapeutic preparations. As with any herbal product during pregnancy, moderation is recommended (Evidence Level C, Traditional use).

What are the side effects of Rosa roxburghii?

Rosa roxburghii is well-tolerated by most individuals with no significant contraindications reported. Mild gastrointestinal upset may occur in sensitive individuals, particularly when consumed on an empty stomach or in large amounts. The high vitamin C content may cause loose stools at elevated doses. Those with known allergies to plants in the Rosaceae family, which includes roses and apples, should exercise caution. Discontinue use if digestive discomfort persists (Evidence Level C).

What is Rosa roxburghii used for in traditional Chinese medicine?

Rosa roxburghii is used in Traditional Chinese Medicine primarily as a digestive tonic to support gastrointestinal health. It has been traditionally employed to address digestive conditions, promote healthy appetite, and strengthen digestive function. The fruit is also valued as a nutrient-dense food source rich in vitamin C, making it beneficial for immune support and general vitality. Modern applications emphasize its exceptional antioxidant density for cellular protection and overall wellness (Evidence Level C, Traditional use).

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Rosa roxburghii, also known as chestnut rose or Cili, is an edible medicinal plant native to southwest China recognized for its high vitamin C content and diverse pharmacological activities [PMID:38735487, PMID:38875459, PMID:36900567].

Contexte

Rosa roxburghii Tratt is a shrub fruit tree endemic to the southwest mountainous areas of China, specifically regions like Guizhou [PMID:37087653, PMID:27618004]. It is classified as both a medicinal and culinary resource [PMID:39278439, PMID:40617042].

Usages traditionnels

Traditionally used in the Miao and Dong regions of Southwest China for relief of sleep disorders, indigestion, anti-inflammation, neurasthenia, and neuroprotection [PMID:40308754]. It is also used to eliminate diet, relieve diarrhea, nourish Yin, invigorate the spleen, dispel wind and dampness, enhance immunity, and treat scurvy, night blindness, cancer, hyperlipidemia, hyperglycemia, and hypertension [PMID:39278439]. The root (Ci Li Gen) is used for abdominal pain, acute bacillary dysentery, and gastroenteritis in humans and livestock [PMID:31877366].

Composés actifs

Key bioactive components include vitamin C (L-ascorbic acid), flavonoids, triterpenes (such as euscaphic acid and kaji-ichigoside F1), polysaccharides (composed of galacturonic acid, glucose, galactose, and arabinose), phenolic acids, organic acids, tannins, carotenoids, amino acids, and essential oils [PMID:38735487, PMID:41828819, PMID:33002536, PMID:41111080, PMID:40308754, PMID:38825289].

Mécanisme d'action

Mechanisms include inhibition of the ROS/NLRP3 signaling pathway to alleviate proinflammatory effects in neutrophils and macrophages [PMID:40617042], activation of PPAR-γ/CX3CR1/Nrf2 and suppression of NF-κB/NLRP3 pathways for antidepressant effects [PMID:40308754], and induction of mitochondrial apoptosis via the ROS/MAPK pathway for anti-cancer activity [PMID:41111080]. Polysaccharides may act by inhibiting α-amylase and α-glucosidase [PMID:33002536].

Preuves cliniques

Preuve DEndotoxemia

Flavonoids reduced IL-6, IL-1β, and TNF-α expression, diminished neutrophil extracellular traps (NETs) release, and reduced macrophage pyroptosis in mice [PMID:40617042]

Preuve DNon-alcoholic fatty liver disease (NAFLD)

Fermented and raw juice ameliorated hyperglycemia, dyslipidemia, and abnormal hepatic function, and restored insulin expression levels in rats [PMID:40458826]; fruit vinegar improved NAFLD by regulating intestinal microbiota in high-fat diet mice [PMID:40873448]

Preuve DColitis/Ulcerative Colitis

Polyphenols and nanogel-encapsulated polyphenols alleviated DSS-induced colitis, preserved intestinal barrier integrity, and inhibited PI3K/Akt/mTOR and NF-κB signaling pathways [PMID:40253185, PMID:41539761]

Preuve DDepression

Kaji-ichigoside F1 showed antidepressant effects in mouse models [PMID:40308754]; fermented juice mitigated CUMS-induced depressive-like behaviors and hippocampal damage by remodeling gut microbiota [PMID:41474946]

Preuve DColorectal Cancer

Euscaphic acid inhibited the viability, proliferation, migration, and invasion of HCT116 and CT26 cells and inhibited graft tumor growth in vivo [PMID:41111080]

Synthèse des preuves

The current evidence is primarily based on in vitro studies and animal models (mice and rats), indicating strong potential for antioxidant, anti-inflammatory, and metabolic regulation, but lacks human clinical trial data.

Sources PubMed

1.PMID: 33002536 (2020) — Extraction optimization, physicochemical properties and antioxidant and hypoglycemic activities of polysaccharides from roxburgh rose (Rosa roxburghii Tratt.) leaves. · International journal of biological macromolecules
2.PMID: 41828819 (2026) — Comparative Metabolomics and Transcriptomics Analysis of Rosa roxburghii Tratt and Rosa kweichonensis var. sterilis. · Molecules (Basel, Switzerland)
3.PMID: 40322293 (2025) — Potential of Fruits to Improve Dyslipidemias: A Pilot Review. · Vascular health and risk management
4.PMID: 40617042 (2025) — The flavonoids of Rosa roxburghii Tratt alleviate endotoxemia progression by inhibiting the proinflammatory effects of neutrophil and macrophage via ROS/NLRP3 signaling pathway. · International immunopharmacology
5.PMID: 37299173 (2023) — Polyploid Induction and Identification of Rosa roxburghii f. eseiosa.

Rosa roxburghii

Sources et citations

Calculer une dose sûre de Rosa roxburghii