Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Scadoxus multiflorus
Tropical African bulb with spectacular orange-red spherical flower heads, used in traditional medicine.
Scadoxus multiflorus is a tropical African bulb used traditionally for fever, infections, and malaria. Modern research focuses on its alkaloids lycorine and narciclasine for antimalarial, anti-inflammatory, antiviral, and anticancer properties, though evidence is limited (Level C) due to significant toxicity concerns.
Lycorine and narciclasine inhibit eukaryotic protein synthesis by binding to the 60S ribosomal subunit, leading to antiproliferative and antiviral effects. Narciclasine induces apoptosis via caspase activation and PI3K/Akt/mTOR pathway inhibition. The alkaloids exhibit anti-inflammatory activity by suppressing NF-κB and COX-2 expression. Antimalarial effects involve disruption of Plasmodium falciparum protein synthesis and potential inhibition of heme polymerization.
Tropical African bulb with spectacular orange-red spherical flower heads, used in traditional medicine.
Scadoxus multiflorus is a tropical African bulb used traditionally for fever, infections, and malaria. Modern research focuses on its alkaloids lycorine and narciclasine for antimalarial, anti-inflammatory, antiviral, and anticancer properties, though evidence is limited (Level C) due to significant toxicity concerns.
Lycorine and narciclasine inhibit eukaryotic protein synthesis by binding to the 60S ribosomal subunit, leading to antiproliferative and antiviral effects. Narciclasine induces apoptosis via caspase activation and PI3K/Akt/mTOR pathway inhibition. The alkaloids exhibit anti-inflammatory activity by suppressing NF-κB and COX-2 expression. Antimalarial effects involve disruption of Plasmodium falciparum protein synthesis and potential inhibition of heme polymerization.