Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Scutellarin suppresses progression by targeting METTL5 [PMID:40425707]; combined with Hedyotis diffusa and cisplatin, it synergistically inhibits progression via NRF2-FTH1 autophagic degradation [PMID:39702302]; and induces ferroptosis in A2780 cells [PMID:39521705].
Induces ferroptosis of HCC cells [PMID:35321425]; exosome-like nanovesicles promote ferroptosis through the Nrf2/SLC7A11/GPX4 pathway [PMID:42209785]; and luteolin inhibits invasion via the miR-6809-5p/FLOT1/FAK pathway [PMID:40857906].
Water extract suppresses growth and lung metastasis by inducing ferroptosis and inhibiting epithelial-mesenchymal transition (EMT) [PMID:42244109]; combined with Hedyotis diffusa, it inhibits proliferation via targeting LMO1 and AKT/Mtor signaling [PMID:37711008].
Self-assembled herbal nanoparticles (with Scleromitrion diffusum) mitigate AKI progression by activating the Nrf2 signaling pathway in mice [PMID:40893687].
Ethanol extract may ameliorate ARDS by inhibiting neutrophil-mediated inflammatory responses [PMID:40122316].
Interactions médicamenteuses
Synthèse des preuves
Sources PubMed
- 1.PMID: 40893687 (2025) — Unveiling the renoprotective mechanisms of self-assembled herbal nanoparticles from Scutellaria barbata and Scleromitrion diffusum in acute kidney injury: A nano-TCM approach. · Acta pharmaceutica Sinica. B
- 2.PMID: 40122316 (2025) — Scutellaria barbata ameliorates acute respiratory distress syndrome by inhibiting neutrophil-mediated inflammatory responses. · Journal of ethnopharmacology
- 3.PMID: 40425707 (2025) — Scutellarin suppresses ovarian cancer progression by targeting METTL5. · Scientific reports
- 4.PMID: 39702302 (2024) — Scutellaria barbata D.Don and Hedyotis diffusa Willd herb pair combined with cisplatin synergistically inhibits ovarian cancer progression through modulating oxidative stress via NRF2-FTH1 autophagic degradation pathway. · Journal of ovarian research
- 5.PMID: 31840605