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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Senna alexandrina pod
Dried pods of senna plant; gentler but longer-lasting laxative action compared to the leaves; widely used in African, Asian and European medicine.
Senna pods (Senna alexandrina) are dried fruits containing sennosides A and B, rhein, and aloe-emodin, which act as prodrugs converted by colonic bacteria into active anthrones. They are used as a stimulant laxative for constipation and bowel preparation, offering a gentler but longer-lasting effect compared to senna leaves. Key active compounds include sennosides, mucilage, and kaempferol.
Sennosides are hydrolyzed by gut β-glucosidases to rheinanthrone, which stimulates colonic peristalsis by activating prostaglandin E2 and nitric oxide pathways, increasing smooth muscle contraction and fluid secretion. Rheinanthrone also inhibits Na+/K+-ATPase and aquaporins, reducing water and electrolyte reabsorption, leading to laxation within 6–12 hours. The mucilage content provides a mild emollient effect, contributing to the gentler profile of pods versus leaves.
Dried pods of senna plant; gentler but longer-lasting laxative action compared to the leaves; widely used in African, Asian and European medicine.
Senna pods (Senna alexandrina) are dried fruits containing sennosides A and B, rhein, and aloe-emodin, which act as prodrugs converted by colonic bacteria into active anthrones. They are used as a stimulant laxative for constipation and bowel preparation, offering a gentler but longer-lasting effect compared to senna leaves. Key active compounds include sennosides, mucilage, and kaempferol.
Sennosides are hydrolyzed by gut β-glucosidases to rheinanthrone, which stimulates colonic peristalsis by activating prostaglandin E2 and nitric oxide pathways, increasing smooth muscle contraction and fluid secretion. Rheinanthrone also inhibits Na+/K+-ATPase and aquaporins, reducing water and electrolyte reabsorption, leading to laxation within 6–12 hours. The mucilage content provides a mild emollient effect, contributing to the gentler profile of pods versus leaves.