Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Moringa oleifera (seeds/bark)
Ayurvedic bark and seed preparation of moringa with anti-inflammatory and anti-arthritic properties.
Shigru (Moringa oleifera seeds/bark) is an Ayurvedic preparation traditionally used for arthritis and inflammation, with modern evidence supporting its anti-inflammatory and anti-arthritic properties. Its primary active compounds include isothiocyanates (e.g., moringin), glucosinolates, niazinin, kaempferol, and phenolic acids, which contribute to its analgesic, antimicrobial, and antioxidant effects. Evidence is limited (Level C) but suggests potential benefit in managing rheumatic conditions.
The anti-inflammatory and anti-arthritic actions of Shigru are mediated through inhibition of NF-κB and COX-2 pathways, reducing pro-inflammatory cytokines such as TNF-α and IL-6. Isothiocyanates, particularly moringin, activate the Nrf2/ARE pathway, enhancing antioxidant enzyme expression and mitigating oxidative stress. Additionally, niazinin and kaempferol exhibit analgesic effects via modulation of opioid and GABAergic receptors, while glucosinolates contribute to antimicrobial activity by disrupting bacterial cell membranes.
Ayurvedic bark and seed preparation of moringa with anti-inflammatory and anti-arthritic properties.
Shigru (Moringa oleifera seeds/bark) is an Ayurvedic preparation traditionally used for arthritis and inflammation, with modern evidence supporting its anti-inflammatory and anti-arthritic properties. Its primary active compounds include isothiocyanates (e.g., moringin), glucosinolates, niazinin, kaempferol, and phenolic acids, which contribute to its analgesic, antimicrobial, and antioxidant effects. Evidence is limited (Level C) but suggests potential benefit in managing rheumatic conditions.
The anti-inflammatory and anti-arthritic actions of Shigru are mediated through inhibition of NF-κB and COX-2 pathways, reducing pro-inflammatory cytokines such as TNF-α and IL-6. Isothiocyanates, particularly moringin, activate the Nrf2/ARE pathway, enhancing antioxidant enzyme expression and mitigating oxidative stress. Additionally, niazinin and kaempferol exhibit analgesic effects via modulation of opioid and GABAergic receptors, while glucosinolates contribute to antimicrobial activity by disrupting bacterial cell membranes.