Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Hydroalcoholic and n-BuOH extracts showed in vitro antifungal activity against C. albicans and C. glabrata; in vivo rat models demonstrated activity against azole-susceptible and resistant species [PMID:21542936, PMID:26007191].
A hydroalcoholic extract of pericarps (ETHOSS) demonstrated in vitro antifungal activity against Trichophyton rubrum, T. mentagrophytes, and T. interdigitale, with the ability to permeate human nails [PMID:33466379].
An observational study of dogs with cutaneous leishmaniasis evaluated a topical ointment containing 2% hederagenin glucoside saponins and 2% chromane-derived hydrazone [PMID:35179617].
Saponin fractions (SAP1, SAP2) from fruit pericarp showed cytotoxic activity against CaCo2 cell lines [PMID:37194675]. Synthetic derivatives of hederagenin demonstrated potent antitumor activity across various human cancer cell lines [PMID:30840925, PMID:27017553, PMID:26476750].
S. saponaria oil promotes cell proliferation, cell migration, and stimulates skin wound-healing effects [PMID:38999621].
Sécurité et effets indésirables
Synthèse des preuves
Sources PubMed
- 1.PMID: 38999621 (2024) — The Biosynthesis Pattern and Transcriptome Analysis of Sapindus saponaria Oil. · Plants (Basel, Switzerland)
- 2.PMID: 40692410 (2025) — Strong and Stiff Sapindus saponaria Seed Shell with Gradient Structure. · Small (Weinheim an der Bergstrasse, Germany)
- 3.PMID: 33932515 (2021) — In vitro biochemical characterization and genotoxicity assessment of Sapindus saponaria seed extract. · Journal of ethnopharmacology
- 4.PMID: 27819730 (2016) — Rhizosphere bacteriome of the medicinal plant Sapindus saponaria L. revealed by pyrosequencing. · Genetics and molecular research : GMR
- 5.PMID: 41771795 (2026) — Extract of Sapindus saponaria L., a Native Amazonian Plant, Impacts Germ Cell Development and Modulates Longevity.