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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Solanum tomentosm
South African nightshade used in Zulu and Xhosa folk medicine for skin conditions, arthritis, and as insect deterrent.
Solanum tomentosum, a South African nightshade, is traditionally used in Zulu and Xhosa medicine for skin conditions, arthritis, and as an insect deterrent. Modern research indicates anti-inflammatory, antimicrobial, and antiparasitic properties, attributed to steroidal alkaloids such as solamargine, solasonine, and tomatidine. Due to potential toxicity, it is primarily used topically under professional guidance.
The steroidal alkaloids solamargine and solasonine exhibit anti-inflammatory activity by inhibiting cyclooxygenase-2 (COX-2) and lipoxygenase pathways, reducing prostaglandin and leukotriene synthesis. Antimicrobial effects involve disruption of microbial cell membranes and inhibition of ergosterol biosynthesis. Antiparasitic actions may be mediated through interference with protozoal tubulin polymerization and mitochondrial function. The presence of tomatidine and other steroidal compounds contributes to modulation of NF-κB signaling and cytokine production.
South African nightshade used in Zulu and Xhosa folk medicine for skin conditions, arthritis, and as insect deterrent.
Solanum tomentosum, a South African nightshade, is traditionally used in Zulu and Xhosa medicine for skin conditions, arthritis, and as an insect deterrent. Modern research indicates anti-inflammatory, antimicrobial, and antiparasitic properties, attributed to steroidal alkaloids such as solamargine, solasonine, and tomatidine. Due to potential toxicity, it is primarily used topically under professional guidance.
The steroidal alkaloids solamargine and solasonine exhibit anti-inflammatory activity by inhibiting cyclooxygenase-2 (COX-2) and lipoxygenase pathways, reducing prostaglandin and leukotriene synthesis. Antimicrobial effects involve disruption of microbial cell membranes and inhibition of ergosterol biosynthesis. Antiparasitic actions may be mediated through interference with protozoal tubulin polymerization and mitochondrial function. The presence of tomatidine and other steroidal compounds contributes to modulation of NF-κB signaling and cytokine production.