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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Stachys lavandulifolia, commonly known as Mountain Tea, is a perennial flowering plant of the Lamiaceae family used in traditional medicine for its anxiolytic, analgesic, and anti-inflammatory properties [PMID:38189318, PMID:40899416].
Contexte
Stachys lavandulifolia Vahl. is an herbaceous plant native to Iran, Turkey, Armenia, Azerbaijan, Iraq, and Turkmenistan [PMID:38189318, PMID:40899416]. In traditional Iranian medicine, it is considered equivalent to Marmazad [PMID:26734474].
Usages traditionnels
It is traditionally used as a mild sedative tea to reduce anxiety, for the treatment of gastrointestinal and respiratory disorders, and for painful conditions [PMID:29844776, PMID:23074920, PMID:29741912].
Composés actifs
Chemical constituents include terpenoids, iridoids, flavonoids (such as apigenin, kumatakenin, and penduletin), and phenylethanoids [PMID:38189318, PMID:29844776]. Essential oil components include alpha-pinene, (E)-caryophyllene, germacrene D, delta-cadinene, alpha-thujone, and myrcene [PMID:40899416, PMID:23593591]. Other identified compounds include betulinic acid, oleanolic acid, rosmarinic acid, and ursolic acid [PMID:20738162].
Mécanisme d'action
The plant may act via the GABAergic and opioidergic systems to produce anticonvulsant and antispasmodic effects [PMID:36589024, PMID:24250359]. In the context of Polycystic Ovary Syndrome (PCOS), it is suggested to influence steroid hormone production, glucose homeostasis, and insulin resistance, targeting genes such as CYP19A1 and the human androgen receptor [PMID:40993927]. It may also decrease progesterone concentrations [PMID:27418911].
Preuves cliniques
Preuve BOccupational Stress in EMTs
A clinical trial using 2g of tea daily for 2 months investigated its effect on occupational stress [PMID:37061348]
Preuve BPrimary Dysmenorrhea
A randomized, double-blind, crossover, placebo-controlled pilot study evaluated the efficacy of standardized capsules in reducing pain [PMID:29741912]
Preuve AVaginal Infections
A systematic review identified Stachys lavandulifolia as an Iranian medicinal plant with anti-vaginal infection properties [PMID:35490427]
Sécurité et effets indésirables
Aqueous extract was found to have no significant hematological changes or mortality in sub-chronic toxicity studies in rats [PMID:25657785]. However, there are concerns regarding the potential pro-oxidant action of antioxidant supplementation [PMID:24027670].
Grossesse et allaitement
In pregnant mice, hydroalcoholic extracts caused a significant increase in absorbed fetuses and decreased fetus length and weight, suggesting potential abortifacient effects [PMID:27418911].
Synthèse des preuves
Evidence consists of a mix of preclinical animal studies (mice/rats), in vitro cancer cell line research, and small-scale clinical trials. While traditional use is widespread, high-level clinical evidence (meta-analyses/large RCTs) is limited.
Sources PubMed
1.PMID: 26734474 (2015) — Stachys lavandulifolia Vahl. and its Relation With Marmazad Activities in Traditional Manuscripts. · Iranian Red Crescent medical journal
2.PMID: 37061348 (2023) — Effect of stachys lavandulifolia on occupational stress in emergency medical technicians. · Explore (New York, N.Y.)
3.PMID: 38189318 (2024) — Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of Stachys lavandulifolia Vahl. · Natural product research
4.PMID: 40899416 (2025) — Pharmacological and toxicological profile of the Stachys lavandulifolia Vahl: a comprehensive review. · Zeitschrift fur Naturforschung. C, Journal of biosciences
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review.
· Infectious disorders drug targets
6.PMID: 41104247 (2025) — Anti-proliferative Activity and Apoptosis Induction of Extracts and Fractions of Stachys lavandulifolia on Lung (H1299), Ovarian (A2780) and Breast (MCF-7) Human Cancer Cell Lines. · Iranian journal of pharmaceutical research : IJPR
7.PMID: 36589024 (2022) — Effect of Hydroalcoholic Extract of Stachys lavandulifolia on Pentylenetetrazole-induced Seizures in Male Mice: The Role of GABAergic and Opioidergic Systems. · Basic and clinical neuroscience
8.PMID: 14611891 (2003) — Anxiolytic effects of Stachys lavandulifolia Vahl on the elevated plus-maze model of anxiety in mice. · Journal of ethnopharmacology
9.PMID: 40400719 (2025) — Investigating the effect aerials part of Stachys Lavandulifolia ointment on 2nd degree burns compared to silver sulfadiazine on male rat. · International journal of burns and trauma
10.PMID: 20738162 (2010) — Extended longevity of Drosophila melanogaster by water and ethanol extracts of Stachys lavandulifolia. · Pharmaceutical biology
11.PMID: 23593591 (2013) — Phytochemical composition of the essential oil of different populations of Stachys lavandulifolia Vahl. · Asian Pacific journal of tropical biomedicine
12.PMID: 34026076 (2021) — A comparative study: Influence of various drying methods on essential oil components and biological properties of Stachys lavandulifolia. · Food science & nutrition
13.PMID: 25657785 (2014) — Acute and subchronic toxicological evaluation of Stachys lavandulifolia aqueous extract in Wistar rats. · Research in pharmaceutical sciences
14.PMID: 29853127 (2018) — In situ green synthesis of Ag nanoparticles on herbal tea extract (Stachys lavandulifolia)-modified magnetic iron oxide nanoparticles as antibacterial agent and their 4-nitrophenol catalytic reduction activity. · Materials science & engineering. C, Materials for biological applications
15.PMID: 29741912 (2018) — Therapeutic Effects of Standardized Formulation of Stachys lavandulifolia Vahl on Primary Dysmenorrhea: A Randomized, Double-Blind, Crossover, Placebo-Controlled Pilot Study. · Journal of alternative and complementary medicine (New York, N.Y.)
16.PMID: 23074920 (2012) — Antimicrobial and antioxidant activities of Stachys lavandulifolia subsp. lavandulifolia essential oil and its infusion. · Natural product communications
17.PMID: 40993927 (2025) — Network Pharmacology Integrated Molecular Docking Analysis Identifies Potential Phytochemicals in Stachys lavandulifolia against Polycystic Ovary Syndrome. · Current pharmaceutical design
18.PMID: 27418911 (2012) — The effect of hydroalcoholic extract of Stachys lavandulifolia vahl on pregnant mice. · EXCLI journal
19.PMID: 29844776 (2017) — Isolation and Identification of Secondary Metabolites from the Aerial Parts of Stachys lavandulifolia Vahl. · Iranian journal of pharmaceutical research : IJPR
20.PMID: 37505651 (2023) — Potent In Vitro and In Vivo Effects of Stachys lavandulifolia Methanolic Extract against Toxoplasma gondii Infection. · Tropical medicine and infectious disease
21.PMID: 24027670 (2013) — Comment on: Anti-Oxidative Stress Activity of Stachys lavandulifolia Aqueous Extract in Humans. · Cell journal
22.PMID: 24250359 (2011) — Spasmolytic effect of stachys lavandulifolia vahl. Crude methanolic extract and fractions on rat ileum. · Iranian journal of pharmaceutical research : IJPR