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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Strychnos nux-vomica
Indian tree; seeds used in Ayurveda at minute doses as nerve tonic after detoxification.
Strychnos nux-vomica is a toxic tree whose seeds contain strychnine and brucine, used in Ayurveda after detoxification (shodhana) as a nerve tonic and digestive stimulant. Its primary uses are for paralysis rehabilitation and as an aphrodisiac, but due to extreme toxicity, only professionally prepared formulations are considered. The key active compounds are strychnine (a glycine receptor antagonist) and brucine, which produce CNS excitation.
Strychnine competitively antagonizes glycine at postsynaptic receptors in the spinal cord and brainstem, leading to disinhibition of motor neurons and increased reflex excitability. Brucine has similar but weaker effects, also acting as a partial agonist at nicotinic acetylcholine receptors. The detoxification process (e.g., boiling in milk) reduces alkaloid content and alters solubility, while low doses may stimulate appetite and digestion via bitter principles and mild cholinergic activity.
Indian tree; seeds used in Ayurveda at minute doses as nerve tonic after detoxification.
Strychnos nux-vomica is a toxic tree whose seeds contain strychnine and brucine, used in Ayurveda after detoxification (shodhana) as a nerve tonic and digestive stimulant. Its primary uses are for paralysis rehabilitation and as an aphrodisiac, but due to extreme toxicity, only professionally prepared formulations are considered. The key active compounds are strychnine (a glycine receptor antagonist) and brucine, which produce CNS excitation.
Strychnine competitively antagonizes glycine at postsynaptic receptors in the spinal cord and brainstem, leading to disinhibition of motor neurons and increased reflex excitability. Brucine has similar but weaker effects, also acting as a partial agonist at nicotinic acetylcholine receptors. The detoxification process (e.g., boiling in milk) reduces alkaloid content and alters solubility, while low doses may stimulate appetite and digestion via bitter principles and mild cholinergic activity.