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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Strychnos spinosa
African thorny tree related to strychnos but primarily food-medicinal; fruit pulp used nutritively while bark is used medicinally for fever, malaria, and toothache.
Strychnos spinosa is an African tree whose fruit pulp is used as a nutritious food, while the bark is employed in traditional medicine for malaria, fever, and toothache. The bark contains trace amounts of strychnine and other alkaloids, along with tannins, flavonoids, and organic acids, which contribute to its antimalarial and antimicrobial properties. Due to potential toxicity, only low doses of bark preparations are recommended, and the herb is contraindicated during pregnancy and lactation.
The antimalarial activity of Strychnos spinosa bark is attributed to loganin and other iridoid glycosides, which may inhibit Plasmodium falciparum growth by interfering with heme detoxification or protein synthesis. Tannins and flavonoids provide antioxidant and anti-inflammatory effects, potentially through scavenging free radicals and modulating NF-κB pathway. The presence of trace strychnine suggests possible neurotoxic effects at high doses, limiting its use. Antimicrobial action against oral pathogens may involve disruption of bacterial cell membranes by tannins and flavonoids.
African thorny tree related to strychnos but primarily food-medicinal; fruit pulp used nutritively while bark is used medicinally for fever, malaria, and toothache.
Strychnos spinosa is an African tree whose fruit pulp is used as a nutritious food, while the bark is employed in traditional medicine for malaria, fever, and toothache. The bark contains trace amounts of strychnine and other alkaloids, along with tannins, flavonoids, and organic acids, which contribute to its antimalarial and antimicrobial properties. Due to potential toxicity, only low doses of bark preparations are recommended, and the herb is contraindicated during pregnancy and lactation.
The antimalarial activity of Strychnos spinosa bark is attributed to loganin and other iridoid glycosides, which may inhibit Plasmodium falciparum growth by interfering with heme detoxification or protein synthesis. Tannins and flavonoids provide antioxidant and anti-inflammatory effects, potentially through scavenging free radicals and modulating NF-κB pathway. The presence of trace strychnine suggests possible neurotoxic effects at high doses, limiting its use. Antimicrobial action against oral pathogens may involve disruption of bacterial cell membranes by tannins and flavonoids.