Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Contexte
Usages traditionnels
Composés actifs
Mécanisme d'action
Preuves cliniques
Administration of crude powder or extracts at 3 g/kg showed a significant reduction in eggs per gram of faeces [PMID:16815639]
Xanthones from S. chirata, specifically 1,5,8-trihydroxy-3-methoxyxanthone (TMX), demonstrated cytotoxic and anti-metastatic potential against breast adenocarcinoma frameworks [PMID:33107489, PMID:33112542]
Methanol extracts provided protection (up to 81%) against paracetamol and galactosamine-induced hepatotoxicity [PMID:10190179]
As part of the polyherbal formulation Ayush-64, S. chirata showed immunomodulatory potential, although it did not limit the lung viral load on its own [PMID:37765142]
Dichloromethane fractions showed significant antimicrobial activity, particularly against Staphylococcus aureus [PMID:20387750]
Interactions médicamenteuses
Synthèse des preuves
Sources PubMed
- 1.PMID: 29076426 (2017) — Swertia chirata: A Comprehensive Review with Recent Advances. · Current pharmaceutical biotechnology
- 2.PMID: 30210007 (2019) — Amarogentin as Topical Anticancer and Anti-Infective Potential: Scope of Lipid Based Vesicular in its Effective Delivery. · Recent patents on anti-infective drug discovery
- 3.PMID: 21338178 (2010) — Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata. · Asian Pacific journal of cancer prevention : APJCP
- 4.PMID: 39318902 (2024) — Anti-inflammatory and Antioxidant Activity of Neem and Kirata-Induced Silver Nanoparticles Against Oral Biofilm: An In Vitro Study. · Cureus
- 5.PMID: 34381094 (2021)