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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Tephrosia vogelii
East African shrub used traditionally for fish poisoning, insecticide, and medicinally for skin conditions and parasites; rotenone-containing plant.
Tephrosia vogelii is an East African shrub traditionally used as a fish poison and insecticide due to its high rotenone content. Modern topical applications include treatment for scabies, lice, and skin infections, but internal use is highly toxic. Key active compounds include rotenone, tephrosin, and deguelin, which act as mitochondrial complex I inhibitors.
Rotenone and related rotenoids inhibit mitochondrial complex I (NADH:ubiquinone oxidoreductase), blocking electron transport and ATP synthesis, leading to cellular energy depletion and death. This mechanism underlies its insecticidal, piscicidal, and acaricidal activity. Topically, rotenone may also disrupt mite and louse nervous systems via similar mitochondrial toxicity, while antimicrobial effects are attributed to membrane disruption by rotenoids and alkaloids.
East African shrub used traditionally for fish poisoning, insecticide, and medicinally for skin conditions and parasites; rotenone-containing plant.
Tephrosia vogelii is an East African shrub traditionally used as a fish poison and insecticide due to its high rotenone content. Modern topical applications include treatment for scabies, lice, and skin infections, but internal use is highly toxic. Key active compounds include rotenone, tephrosin, and deguelin, which act as mitochondrial complex I inhibitors.
Rotenone and related rotenoids inhibit mitochondrial complex I (NADH:ubiquinone oxidoreductase), blocking electron transport and ATP synthesis, leading to cellular energy depletion and death. This mechanism underlies its insecticidal, piscicidal, and acaricidal activity. Topically, rotenone may also disrupt mite and louse nervous systems via similar mitochondrial toxicity, while antimicrobial effects are attributed to membrane disruption by rotenoids and alkaloids.