Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
PubMed · Terminalia catappa Fruit Extract Reverses Streptozotocin-Induced Diabetic Retinopathy in Rats. (2021)
PubMed · <i>Terminalia catappa</i> attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up-regulation of <i>in vivo</i> antioxidant armouries. (2023)
Révisé par : HerbAlly Editorial Team, Medical herbalists and healthcare professionals
Dernière mise à jour : April 2026
Calculer une dose sûre de Terminalia catappa
Calculateur gratuit de posologie — doses adultes et enfants selon le poids.
Terminalia catappa (Terminalia catappa) est connu en anglais sous les noms Amandier des Indes, Amandier de mer, Amandier tropical. Il est traditionnellement utilisé pour maladie du foie, hépatite, cicatrisation des plaies.
Terminalia catappa est-il sûr pendant la grossesse ?
Terminalia catappa n'est pas recommandé pendant la grossesse. Consultez votre professionnel de santé pour des alternatives.
Terminalia catappa interagit-il avec les médicaments ?
Terminalia catappa ne présente pas d'interaction médicamenteuse majeure bien documentée dans notre base, mais informez toujours votre professionnel de santé de tous les compléments que vous prenez.
Quels sont les effets secondaires de Terminalia catappa ?
Dosage: 5-10 g dried leaves as tea twice daily; exceeding may cause gastrointestinal upset.. Pregnancy: Unsafe due to potential uterine stimulant effects from tannins.. Contraindicated in liver disease due to high tannin content which may exacerbate hepatic stress.. Side effects: constipation with excessive tannin intake; rare allergic reactions.
Comment calculer une dose sûre de Terminalia catappa ?
Utilisez le calculateur de posologie gratuit d'HerbAlly — saisissez la dose adulte de référence pour Terminalia catappa, plus l'âge et le poids, pour obtenir une estimation pédiatrique selon Clark / Young. Ne dépassez jamais la dose adulte.
Fiche d'information compilée à partir de PubMed
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Terminalia catappa, known as tropical almond, is a multipurpose tree with documented nutritional value and various pharmacological benefits, including antioxidant and antidiabetic activities [PMID:39844979, PMID:26392705].
Contexte
Terminalia catappa L. (family Combretaceae) is a globally distributed, salinity-tolerant nut-yielding tree used for avenue planting, agroforestry, and as a source of small timber [PMID:39844979, PMID:41599698].
Usages traditionnels
It is used in ethnopharmacological applications as a heart stimulator, anti-diarrhoeal, bactericidal, anti-parasitic, and anti-stress agent, and to treat angina pectoris, asthma attacks, and bronchitis [PMID:41599698]. Leaves are used for hypertension, diabetes, cough, and jaundice, while the bark is used for diarrhea, dysentery, and abscesses [PMID:38465010].
Composés actifs
Key phytoconstituents include phenols, flavonoids, carotenoids [PMID:26392705], alkaloids, tannins, steroids, cardiac glycosides [PMID:38566161], and saponins and terpenoids [PMID:28969774]. Specific identified compounds in leaf extracts include gallic acid, orientin, vitexin, ellagic acid [PMID:41002978], and α-punicalagin [PMID:39252640]. Fruits contain betalains (betacyanin and betaxanthin) [PMID:41956050].
Mécanisme d'action
Proposed mechanisms for antidiabetic activity include reduction of oxidative stress, inflammation, angiogenesis, and lipid profile correction [PMID:28000229]. In C. elegans, leaf extract improves lipid metabolism and antioxidant activity via the AMPK signaling pathway [PMID:38275634]. In melanoma cells, it inhibits metastasis by downregulating the p-Src and β-catenin pathway [PMID:36238547]. Antihypertensive effects are mediated via modulation of angiotensin-1-converting enzyme (ACE) activity and the H2S/NO/cGMP signaling pathway [PMID:37002876].
Preuves cliniques
Preuve DDiabetes/Hyperglycemia
Leaf extracts significantly reduced blood glucose, glycosylated hemoglobin, and increased insulin levels in STZ-treated rats [PMID:31303829, PMID:39827649].
Preuve DDiabetic Retinopathy
Hydroalcoholic fruit extract reversed streptozotocin-induced diabetic retinopathy in rats [PMID:33121423].
Preuve DObesity/Hyperlipidemia
Leaf extract reduced liver and adipose lipid accumulation and inflammation in HFD-induced obese mice [PMID:41002978]. Fruit extracts showed anti-atherosclerotic and antihyperlipidemic roles in rat models [PMID:37810701].
Preuve DHypertension
Fruit-supplemented diets lowered blood pressure and modulated ACE and arginase activity in L-NAME-induced hypertensive rats [PMID:37002876].
Preuve DMelanoma
Leaf extracts inhibited the migration and invasion of A2058 and A375 melanoma cells in vitro [PMID:36238547].
Preuve BHaemonchus contortus (Parasitism)
Sécurité et effets indésirables
A toxicological evaluation of aqueous leaf extract was conducted in pregnant rats [PMID:38465010]. Leaf extract showed no cytotoxicity in RAW 264.7 mouse macrophages [PMID:39252640].
Grossesse et allaitement
A study was performed to evaluate the toxicological profiles of aqueous leaf extract in pregnant rats [PMID:38465010].
Synthèse des preuves
The majority of evidence is based on in vitro studies and animal models (rats, mice, C. elegans), with one controlled clinical trial in lambs. There is a lack of human clinical trial data.
2.PMID: 26392705 (2015) — An updated review of Terminalia catappa. · Pharmacognosy reviews
3.PMID: 41599698 (2026) — Tropical Almond Tree (Terminalia catappa L.): A Comprehensive Review of the Phytochemical Composition, Bioactivities and Economic Potential. · Pharmaceuticals (Basel, Switzerland)
4.PMID: 38275634 (2023) — Indian Almond (Terminalia catappa Linn.) Leaf Extract Extends Lifespan by Improving Lipid Metabolism and Antioxidant Activity Dependent on AMPK Signaling Pathway in Caenorhabditis elegans under High-Glucose-Diet Conditions. · Antioxidants (Basel, Switzerland)
5.PMID: 38628750 (2024) — Graphene oxide doping in tropical almond (terminalia catappa L.) fruits extract mediated green synthesis of TiO2 nanoparticles for improved DSSC power conversion efficiency.
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
Seed and pulp extracts showed anthelmintic activity in vitro and in vivo in lambs [PMID:28969774].
· Heliyon
6.PMID: 38165984 (2024) — Changes in nutritional, health benefits, and pharmaceutical potential of raw and roasted tropical almond (Terminalia catappa Linn.) nuts from Nigeria. · PloS one
7.PMID: 28056164 (2017) — Analysis of sea almond (Terminalia catappa) cracking sites used by wild Burmese long-tailed macaques (Macaca fascicularis aurea). · American journal of primatology
8.PMID: 41002978 (2025) — Phenolic-Rich Indian Almond (Terminalia catappa Linn) Leaf Extract Ameliorates Lipid Metabolism and Inflammation in High-Fat Diet (HFD)-Induced Obese Mice. · Metabolites
9.PMID: 23885412 (2012) — Potential application of extracts from Indian almond (Terminalia catappa Linn.) leaves in Siamese fighting fish (Betta splendens Regan) culture. · Communications in agricultural and applied biological sciences
10.PMID: 28000229 (2017) — Proposed mechanisms of Terminalia catappa in hyperglycaemia and associated diabetic complications. · The Journal of pharmacy and pharmacology
11.PMID: 36238547 (2022) — Terminalia catappa leaf extracts inhibited metastasis of A2058 and A375 melanoma cells via downregulating p-Src and β-catenin pathway in vitro. · Frontiers in pharmacology
12.PMID: 26396409 (2015) — Physicochemical properties of Malaysian-grown tropical almond nuts (Terminalia catappa). · Journal of food science and technology
13.PMID: 33121423 (2021) — Terminalia catappa Fruit Extract Reverses Streptozotocin-Induced Diabetic Retinopathy in Rats. · Endocrine, metabolic & immune disorders drug targets
14.PMID: 29805208 (2018) — Effects of lipid extraction on nutritive composition of winged bean (Psophocarpus tetragonolobus), rubber seed (Hevea brasiliensis), and tropical almond (Terminalia catappa). · Veterinary world
15.PMID: 38098904 (2023) — Anti-quorum Sensing of Terminalia catappa and Murraya koenigii Against Streptococcus mutans. · Cureus
16.PMID: 31303829 (2019) — Phytotherapeutic efficacy of the medicinal plant Terminalia catappa L. · Saudi journal of biological sciences
17.PMID: 38465010 (2023) — Toxicological evaluation of aqueous leaf extract of Terminalia catappa linn (combretaceae) in pregnant rats. · The Pan African medical journal
18.PMID: 37810701 (2023) — Anti-Atherosclerosis and Anti-Hyperlipidemia Functions of Terminalia catappa Fruit. · ACS omega
19.PMID: 38566161 (2024) — Phytochemical characterization, antimicrobial and antioxidant activities of Terminalia catappa methanol and aqueous extracts. · BMC complementary medicine and therapies
20.PMID: 36625008 (2023) — Terminalia catappa attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up-regulation of in vivo antioxidant armouries. · Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
21.PMID: 37002876 (2023) — Antioxidant-rich Terminalia catappa fruit exerts antihypertensive effect via modulation of angiotensin-1-converting enzyme activity and H2S/NO/cGMP signalling pathway in Wistar rats. · Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
22.PMID: 26139937 (2015) — The effect of thermal processing on protein quality and free amino acid profile of Terminalia catappa (Indian Almond) seed. · Journal of food science and technology
23.PMID: 26226895 (2015) — The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae). · Inflammopharmacology
24.PMID: 39827649 (2025) — Terminalia catappa aqueous extract reduces hyperglycaemia and oxidative stress in diabetic-hypercholesterolemic rats. · Journal of Ayurveda and integrative medicine
25.PMID: 37766705 (2023) — Counteractive role of Terminalia catappa leaf extract on hematological and coagulation disturbance in Type 2 diabetic rats. · Veterinary world
26.PMID: 25317204 (2014) — Effect of roasting conditions on color development and Fourier transform infrared spectroscopy (FTIR-ATR) analysis of Malaysian-grown tropical almond nuts (Terminalia catappa L.). · Chemistry Central journal
27.PMID: 41956050 (2026) — NADES-based extraction of betalains from Terminalia catappa: impact on bioaccessibility, antioxidant capacity, and antimicrobial efficacy. · Food chemistry
28.PMID: 28969774 (2017) — Terminalia catappa: Chemical composition, in vitro and in vivo effects on Haemonchus contortus. · Veterinary parasitology
29.PMID: 39252640 (2024) — Validation of Active Compound of Terminalia catappa L. Extract and Its Anti-Inflammatory and Antioxidant Properties by Regulating Mitochondrial Dysfunction and Cellular Signaling Pathways. · Journal of microbiology and biotechnology
30.PMID: 37508328 (2023) — In Vitro Antioxidant and Antitrypanosomal Activities of Extract and Fractions of Terminalia catappa. · Biology