Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Ternstroemia tepezapote
Mexican and Central American flowering tree used as a sedative and anxiolytic tea; widely sold in Mexican markets and pharmacies for insomnia and anxiety.
Tila (Ternstroemia tepezapote) is a flowering tree native to Mexico and Central America, traditionally used as a sedative and anxiolytic tea for insomnia and anxiety. Its primary active compounds include flavonoids (kaempferol, quercetin), the triterpenoid saponin ternstroside, and other saponins, which are believed to mediate its calming and antispasmodic effects. Modern evidence is limited (Level C), with pilot studies supporting mild sedative and anxiolytic activity, though rigorous clinical trials are lacking.
The anxiolytic and sedative effects of Tila are primarily attributed to flavonoid compounds such as kaempferol and quercetin, which may modulate GABA-A receptors by enhancing chloride ion conductance, thereby increasing inhibitory neurotransmission. Ternstroside has demonstrated affinity for the benzodiazepine binding site on GABA-A receptors, potentiating GABAergic activity without direct receptor activation. Additionally, anti-inflammatory effects are mediated through inhibition of cyclooxygenase-2 (COX-2) and nuclear factor-kappa B (NF-κB) pathways, while antispasmodic actions involve calcium channel blockade in smooth muscle cells.
Mexican and Central American flowering tree used as a sedative and anxiolytic tea; widely sold in Mexican markets and pharmacies for insomnia and anxiety.
Tila (Ternstroemia tepezapote) is a flowering tree native to Mexico and Central America, traditionally used as a sedative and anxiolytic tea for insomnia and anxiety. Its primary active compounds include flavonoids (kaempferol, quercetin), the triterpenoid saponin ternstroside, and other saponins, which are believed to mediate its calming and antispasmodic effects. Modern evidence is limited (Level C), with pilot studies supporting mild sedative and anxiolytic activity, though rigorous clinical trials are lacking.
The anxiolytic and sedative effects of Tila are primarily attributed to flavonoid compounds such as kaempferol and quercetin, which may modulate GABA-A receptors by enhancing chloride ion conductance, thereby increasing inhibitory neurotransmission. Ternstroside has demonstrated affinity for the benzodiazepine binding site on GABA-A receptors, potentiating GABAergic activity without direct receptor activation. Additionally, anti-inflammatory effects are mediated through inhibition of cyclooxygenase-2 (COX-2) and nuclear factor-kappa B (NF-κB) pathways, while antispasmodic actions involve calcium channel blockade in smooth muscle cells.