Tilia Tomentosa Herb (Tilia tomentosa): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Tilia tomentosa work as a sedative?

Tilia tomentosa contains flavonoids including tiliroside, kaempferol, and quercetin, which are believed to modulate GABA receptors in the central nervous system, producing calming and sedative effects. These compounds, along with volatile oils, contribute to the herb's antispasmodic and anxiolytic properties. While the exact mechanism requires further research, the GABAergic activity is thought to be the primary pathway for its anxiety-reducing and sleep-promoting effects. Evidence level: C.

Does Tilia tomentosa interact with medications?

Tilia tomentosa may interact with central nervous system depressants, including benzodiazepines, barbiturates, and sleep medications, potentially enhancing sedative effects and increasing drowsiness. Due to potential cardiac effects at higher doses, it may also interact with heart medications such as antiarrhythmics or antihypertensives. Patients taking prescription medications should consult a qualified healthcare provider before using Tilia tomentosa. Evidence level: C.

What is the recommended dosage for Tilia tomentosa tea?

The standard adult dosage for Tilia tomentosa is 2-4 grams of dried flowers prepared as a tea. Steep the dried flowers in boiling water for 10-15 minutes before straining. This preparation may be consumed up to three times daily for anxiety, insomnia, or respiratory support. Dosages exceeding this range should be avoided due to potential cardiac effects. Evidence level: Traditional.

Is Tilia tomentosa safe during pregnancy?

Tilia tomentosa is considered unsafe during pregnancy and should be avoided. The herb's sedative properties and potential effects on smooth muscle and cardiac function pose risks during pregnancy. Women who are pregnant, planning to become pregnant, or breastfeeding should not use this herb without professional medical supervision. Evidence level: C.

What is Tilia tomentosa used for in herbal medicine?

Tilia tomentosa, or silver-leafed linden, is traditionally used in Balkan folk medicine as a sedative nervine for anxiety and insomnia. It also serves as a remedy for colds, fevers, and respiratory conditions due to its antispasmodic and diaphoretic properties. The dried flowers are most commonly prepared as a tea for these therapeutic applications. Evidence level: C.

Can Tilia tomentosa cause heart problems?

Tilia tomentosa can affect cardiac function when consumed in excessive amounts and is contraindicated for individuals with pre-existing heart disease. Potential cardiac effects include palpitations or arrhythmias at high doses. Those with cardiovascular conditions should avoid this herb or use it only under professional medical guidance. Moderate dosing within the recommended 2-4 gram range minimizes this risk. Evidence level: C.

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Tilia tomentosa (silver linden) is a medicinal plant used traditionally for its sedative and anti-spasmodic properties [PMID:26144285, PMID:34684506].

Contexte

Tilia tomentosa Moench, also known as silver linden, basswood, or lime tree, is a tree species used in traditional medicine, particularly in European and Latin American contexts [PMID:28954857, PMID:26144285, PMID:7990504].

Usages traditionnels

It has been used for centuries as a sedative compound [PMID:26144285], as a tranquilizer in Latin America via inflorescence infusions [PMID:7990504], and as an anti-spasmodic in popular medicine [PMID:34684506]. Leaves are also used in the treatment of bronchitis and the common cold [PMID:15507365].

Composés actifs

The plant contains flavonoids, including quercetin, kaempferol, apigenin, luteolin, rutin, and tiliroside [PMID:30638062, PMID:26135753]. Other identified compounds include organic acids (ellagic, shikimic, and quinic acid), pentacyclic triterpenes (oleanolic and maslinic acid), and pectic polysaccharides [PMID:30638062, PMID:28732735].

Mécanisme d'action

Bud extracts inhibit hippocampal neuronal firing by activating GABAA and benzodiazepine receptors [PMID:26144285]. Pectic polysaccharides stimulate Peyer's patch immune cells and human blood T-cell populations [PMID:28732735]. Certain flavonoids from leaves exhibit antinociceptive and anti-inflammatory activities [PMID:15507365].

Preuves cliniques

Preuve DIntestinal Contractility

Flower extract induced marked relaxation in mouse ileal specimens [PMID:34684506].

Preuve DAnxiety/Sedation

A complex flavonoid fraction from inflorescences showed clear anxiolytic effects in mouse elevated plus-maze and holeboard tests [PMID:7990504]. Bud extracts activated chloride currents in mouse hippocampal neurons [PMID:26144285].

Preuve DInflammation/Pain

Kaempferol-3,7-O-alpha-dirhamnoside and quercetin-3,7-O-alpha-dirhamnoside from leaves showed potent antinociceptive and anti-inflammatory activity in mice [PMID:15507365].

Preuve DImmune Response

Acidic polysaccharide complexes stimulated ex vivo human blood T-cell populations and induced IL-6 production [PMID:28732735].

Synthèse des preuves

The current evidence is based primarily on in vitro studies and animal models (Level D), demonstrating sedative, anti-inflammatory, and intestinal relaxant activities. No human clinical trials were provided in the source abstracts.

Sources PubMed

1.PMID: 28954857 (2017) — Do linden trees kill bees? Reviewing the causes of bee deaths on silver linden (Tilia tomentosa). · Biology letters
2.PMID: 34684506 (2021) — Influence of Tilia tomentosa Moench Extract on Mouse Small Intestine Neuromuscular Contractility. · Nutrients
3.PMID: 35622652 (2022) — Impact of Soil Pollution on Melliferous Plants. · Toxics
4.PMID: 41736750 (2026) — The suitability of structural soil for the development of trees growing in urban areas. · PeerJ
5.PMID: 35947287 (2022) — Spray-drying Microencapsulation of an Extract from Tilia tomentosa Moench Flowers: Physicochemical Characterization and in Vitro Intestinal Activity. · Plant foods for human nutrition (Dordrecht, Netherlands)

Tilia Tomentosa Herb

Sources et citations

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