Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Peganum harmala var. africana
North African variety of Syrian rue used in Tunisian and Libyan folk medicine as incense, antimicrobial, and psychoactive.
Tunisian Harmel (Peganum harmala var. africana) is a North African variety of Syrian rue traditionally used as incense, antimicrobial, and psychoactive agent. Its primary active compounds include harmine, harmaline, harmalol, and vasicine, which contribute to its MAOI, anthelmintic, and antimicrobial properties. Due to significant toxicity and abortifacient effects, it requires expert supervision and is contraindicated in pregnancy.
Harmine and harmaline are reversible inhibitors of monoamine oxidase A (MAO-A), increasing levels of serotonin, norepinephrine, and dopamine in the brain. These β-carboline alkaloids also interact with 5-HT2A receptors, contributing to psychoactive effects. Additionally, harmine and vasicine exhibit antimicrobial activity by disrupting bacterial cell membranes and inhibiting DNA gyrase, while anthelmintic effects are mediated through paralysis of parasitic worms via GABAergic and cholinergic pathways.
North African variety of Syrian rue used in Tunisian and Libyan folk medicine as incense, antimicrobial, and psychoactive.
Tunisian Harmel (Peganum harmala var. africana) is a North African variety of Syrian rue traditionally used as incense, antimicrobial, and psychoactive agent. Its primary active compounds include harmine, harmaline, harmalol, and vasicine, which contribute to its MAOI, anthelmintic, and antimicrobial properties. Due to significant toxicity and abortifacient effects, it requires expert supervision and is contraindicated in pregnancy.
Harmine and harmaline are reversible inhibitors of monoamine oxidase A (MAO-A), increasing levels of serotonin, norepinephrine, and dopamine in the brain. These β-carboline alkaloids also interact with 5-HT2A receptors, contributing to psychoactive effects. Additionally, harmine and vasicine exhibit antimicrobial activity by disrupting bacterial cell membranes and inhibiting DNA gyrase, while anthelmintic effects are mediated through paralysis of parasitic worms via GABAergic and cholinergic pathways.