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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Senna hebecarpa
Native North American senna used by Indigenous peoples and later by Eclectic physicians as gentle laxative.
Wild Senna (Senna hebecarpa) is a native North American herb traditionally used by Indigenous peoples and Eclectic physicians as a gentle stimulant laxative. Its primary active compounds are anthraquinone glycosides (sennosides), which are converted by gut microbiota to active metabolites that stimulate colonic peristalsis. Modern evidence supports its use for short-term constipation relief, with additional anti-inflammatory properties attributed to flavonoids and tannins.
Sennosides are hydrolyzed by colonic bacteria to rheinanthrone, which activates the enteric nervous system via stimulation of A2B adenosine receptors and increases colonic motility. Rheinanthrone also inhibits Na+/K+ ATPase and water absorption, leading to fluid accumulation and laxation. Anti-inflammatory effects may involve flavonoid-mediated inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis.
Native North American senna used by Indigenous peoples and later by Eclectic physicians as gentle laxative.
Wild Senna (Senna hebecarpa) is a native North American herb traditionally used by Indigenous peoples and Eclectic physicians as a gentle stimulant laxative. Its primary active compounds are anthraquinone glycosides (sennosides), which are converted by gut microbiota to active metabolites that stimulate colonic peristalsis. Modern evidence supports its use for short-term constipation relief, with additional anti-inflammatory properties attributed to flavonoids and tannins.
Sennosides are hydrolyzed by colonic bacteria to rheinanthrone, which activates the enteric nervous system via stimulation of A2B adenosine receptors and increases colonic motility. Rheinanthrone also inhibits Na+/K+ ATPase and water absorption, leading to fluid accumulation and laxation. Anti-inflammatory effects may involve flavonoid-mediated inhibition of cyclooxygenase (COX) and lipoxygenase (LOX) pathways, reducing prostaglandin and leukotriene synthesis.