How does wolfberry improve eyesight?

Wolfberry (Lycium barbarum) supports vision primarily through its high concentration of zeaxanthin and beta-carotene. These carotenoids accumulate in the retina, specifically the macula, acting as antioxidants that filter harmful blue light and neutralize free radicals. Traditional Chinese Medicine attributes this effect to the herb's ability to nourish liver blood, which is believed to directly benefit the eyes. Evidence level: C.

Can I take goji berries with warfarin?

You should avoid consuming wolfberry (goji berry) if you take warfarin. Wolfberry contains compounds that may increase the risk of bleeding by enhancing the anticoagulant effects of warfarin. Case reports suggest it can elevate INR levels, potentially leading to hemorrhage. Patients on blood thinners should consult a healthcare provider before adding this herb to their diet. Evidence level: C.

What is the recommended daily dosage for dried goji berries?

The standard adult dosage for dried wolfberries is 10 to 15 grams daily, roughly equivalent to a small handful. For concentrated extracts, a dosage of 500 to 1000 mg per day is common. The berries can be eaten raw, cooked in soups, or steeped as a tea. It is best to start with a lower amount to assess digestive tolerance. Evidence level: Traditional.

Is wolfberry safe to eat during pregnancy?

Yes, wolfberry is generally considered safe for consumption during pregnancy when eaten in moderate food amounts. In Traditional Chinese Medicine, it is used to nourish liver and kidney yin. However, pregnant women should avoid high medicinal doses and consult a healthcare provider before use, especially if taking other medications or experiencing digestive issues. Evidence level: Traditional.

What are the side effects of eating goji berries?

While generally well-tolerated, wolfberry may cause mild gastrointestinal upset in some individuals, particularly when consumed in large quantities. Rare cases of hypersensitivity or allergic skin reactions have been reported. People with high fever or diarrhea should avoid this herb as it may exacerbate these conditions according to Traditional Chinese Medicine principles. Evidence level: Traditional.

Baie de Goji (Lycium barbarum)

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Wolfberry (Lycium barbarum), also known as goji berry, is a traditional Chinese medicinal herb and functional food used to promote health and treat various diseases [PMID:33907670, PMID:38107149].

Contexte

Lycium barbarum is a genus of the Solanaceae family, where the fruits, roots, stems, and leaves are utilized for both food and medicinal purposes [PMID:38107149, PMID:34083720].

Usages traditionnels

In Traditional Chinese Medicine (TCM), it is used to enhance immune system function, improve eyesight, protect the liver, boost sperm production, improve circulation, and treat tinnitus, impotence, spermatorrhea, and blood deficiency [PMID:33907670, PMID:38657878, PMID:41059192].

Composés actifs

Key bioactive components include Lycium barbarum polysaccharides (LBPs), carotenoids (such as zeaxanthin dipalmitate), polyphenols, betaine, flavonoids, glycopeptides, and phenolamides [PMID:31163996, PMID:37282868, PMID:38138534, PMID:38541744, PMID:38657878, PMID:41059192].

Mécanisme d'action

Mechanisms include inhibition of the PI3K/AKT1 signaling pathway in lung cancer [PMID:36591458], inhibition of the ERK, AKT, and CyclinD pathways in oral cancer [PMID:36761830], and regulation of the AMPK/SIRT1/PGC1α signaling pathway to inhibit muscle atrophy [PMID:38778385]. It also acts by reducing oxidative stress, inhibiting lipid peroxidation and ferroptosis in the brain [PMID:37182278, PMID:39644762], and increasing the abundance of Akkermansia muciniphila to increase YAP1 expression in the liver [PMID:36468767].

Preuves cliniques

Preuve AGlucose and Lipid Metabolism

Daily consumption of LBP significantly regulates serum triglyceride (TG), fasting blood glucose, and low-density lipoprotein (LDL) [PMID:34213407]

Preuve BPeriodontitis

Evaluated as a mouthwash compared to chlorhexidine for managing periodontitis [PMID:39640061]

Preuve DFemale Fertility

Aqueous extract significantly increased pregnancy and live birth rates in naturally aged female mice [PMID:39224078]

Preuve DMale Reproductive Injury

Protective effects against anti-tuberculosis drug-induced reproductive injury in mice [PMID:40761284]

Preuve DMuscle Atrophy

Gouqi-derived nanovesicles (GqDNVs) inhibited dexamethasone-induced muscle atrophy in mice [PMID:38778385]

Preuve DAnxiety Disorders

Wolfberry glycopeptide (LbGp) relieved anxiety-like and depressive behaviors in chronic restrain stress mice [PMID:37182278]

Sécurité et effets indésirables

Most herbs and supplements can be safely taken in moderation, but some reports indicate risks of bleeding events when used concurrently with certain medications [PMID:32478963].

Interactions médicamenteuses

Wolfberry is listed among herbs and dietary supplements that may interact with warfarin, with some reports indicating potentiation and an increased risk of bleeding [PMID:32478963].

Posologie et administration

TCM suggests preparation as a decoction or ground into a powder and mixed with other herbs [PMID:33907670]. Consult a healthcare provider.

Synthèse des preuves

Evidence ranges from high-level meta-analyses for metabolic regulation to preliminary animal and in-vitro studies for neuroprotection, oncology, and reproductive health.

Sources PubMed

1.PMID: 38778385 (2024) — Gouqi-derived nanovesicles (GqDNVs) inhibited dexamethasone-induced muscle atrophy associating with AMPK/SIRT1/PGC1α signaling pathway. · Journal of nanobiotechnology
2.PMID: 32478963 (2021) — Warfarin and food, herbal or dietary supplement interactions: A systematic review. · British journal of clinical pharmacology
3.PMID: 33907670 (2021) — Health benefits of wolfberry (Gou Qi Zi, Fructus barbarum L.) on the basis of ancient Chineseherbalism and Western modern medicine. · Avicenna journal of phytomedicine
4.PMID: 39224078 (2024) — Lycium barbarum berry extract improves female fertility against aging-related oxidative stress in the ovary. · Food & function
5.PMID: 36591458 (2022)

Baie de Goji

Sources et citations