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Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Xing Ren (Prunus armeniaca), specifically the apricot seed, is used in traditional medicine for respiratory and intestinal disorders [PMID:36806484, PMID:38323080].
Contexte
Prunus armeniaca L., commonly known as the apricot tree, is a species of the Rosaceae family [PMID:35890519, PMID:30728542]. The seed, known as Armeniacae Semen Amarum or Kuxingren in Chinese, is recognized as an herbal medicinal product in Chinese and Korean pharmacopeias [PMID:35890519, PMID:36806484].
Usages traditionnels
It is traditionally used in Traditional Chinese Medicine (TCM) to relieve cough and asthma, moisten the intestines, and treat constipation [PMID:36806484, PMID:38323080]. Other reported medicinal uses include applications as an antipyretic, antiseptic, anti-inflammatory, emetic, and ophthalmic remedy [PMID:35890519].
Composés actifs
Active components include amygdalin, bitter almond oil, essential oil, proteins, vitamins, and carbohydrates [PMID:36806484]. The kernel oil contains unsaturated fatty acids (high proportion of oleic acids), phenols, and tocopherols [PMID:36778095], as well as steroids, flavonoids, terpenoids, alkaloids, and cardiac glycosides [PMID:39544277].
Mécanisme d'action
The kernel oil is noted for anti-inflammatory and antioxidant effects [PMID:39170485]. Aqueous extracts of the leaves (PAAE) have demonstrated the ability to lower blood pressure parameters in hypertensive rats [PMID:35702770].
Preuves cliniques
Preuve DHypertension
Aqueous extract of P. armeniaca leaves lowered blood pressure in L-NAME-induced hypertensive rats without affecting normotensive rats [PMID:35702770]
Preuve DNeuropathic Pain
Apricot kernel oil showed analgesic effects in rats with chronic constriction injury-induced neuropathic pain [PMID:39170485]
Preuve CCancer
Reviews suggest the kernel may help fight against various diseases such as cancer and cancer immunotherapy [PMID:35892769, PMID:35890519]
Sécurité et effets indésirables
Prolonged use of a TCM supplement containing apricot kernel, licorice root, and caffeine was potentially linked to tachycardia-induced cardiomyopathy (TIC) in a 62-year-old male [PMID:39845 la8485]. The seeds contain amygdalin [PMID:35919360], and cyanide poisoning is associated with the 'bitter-almond' smell [PMID:15317203].
Interactions médicamenteuses
The safety of TCM herbal remedies containing apricot kernel requires careful consideration when used with modern medications [PMID:39845213].
Synthèse des preuves
The evidence consists primarily of review articles (Level C) and animal/in vitro studies (Level D). There is a lack of high-level clinical trial data (Level A or B) in the provided abstracts.
Sources PubMed
1.PMID: 35892769 (2022) — Apricot Kernel: Bioactivity, Characterization, Applications, and Health Attributes. · Foods (Basel, Switzerland)
3.PMID: 36778095 (2023) — Apricot kernel characterization, oil extraction, and its utilization: a review. · Food science and biotechnology
4.PMID: 35702770 (2023) — Antihypertensive Activity of Prunus armeniaca in Hypertensive Rats. · Cardiovascular & hematological agents in medicinal chemistry
5.PMID: 30728542 (2019) — Production, pomological and nutraceutical properties of apricot. · Journal of food science and technology
Sources gouvernementales
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
6.PMID: 35890519 (2022) — Anticancer Potential and Other Pharmacological Properties of Prunus armeniaca L.: An Updated Overview. · Plants (Basel, Switzerland)
7.PMID: 39170485 (2024) — Analgesic effect of apricot kernel oil on neuropathic pain in rats. · Heliyon
8.PMID: 36806484 (2023) — Phytochemistry and pharmacology of Armeniacae semen Amarum: A review. · Journal of ethnopharmacology
9.PMID: 15317203 (2004) — Suicide by cyanide: 17 deaths. · Journal of forensic sciences
10.PMID: 38323080 (2024) — Armeniacae semen amarum: a review on its botany, phytochemistry, pharmacology, clinical application, toxicology and pharmacokinetics. · Frontiers in pharmacology
11.PMID: 35919360 (2022) — Rapid quantitative typing spectra model for distinguishing sweet and bitter apricot kernels. · Food science and biotechnology
12.PMID: 39544277 (2024) — Unlocking the Therapeutic and Antimicrobial Potential of Prunus armeniaca L. Seed Kernel Oil. · International journal of food science