How does yarrow help heal wounds?

Yarrow works through compounds like achillein and flavonoids, which possess hemostatic properties that help stop bleeding. Its volatile oils, specifically chamazulene, provide anti-inflammatory and antiseptic benefits that support tissue repair. This combination allows yarrow to constrict blood vessels and promote clotting, making it a traditional remedy for treating cuts, abrasions, and nosebleeds (Evidence Level: B).

Does yarrow interact with blood thinners?

Yes, yarrow interacts with anticoagulant and antiplatelet medications such as warfarin, clopidogrel, or aspirin. Because yarrow affects blood clotting mechanisms, taking it alongside these drugs may increase the risk of bleeding or bruising. Patients on blood thinners should avoid yarrow supplements unless specifically directed by a healthcare provider (Evidence Level: C).

Is yarrow safe to take during pregnancy?

Yarrow is considered unsafe during pregnancy and should be avoided. The herb has emmenagogue properties, meaning it can stimulate uterine contractions and menstrual flow, potentially leading to miscarriage or premature labor. Women who are pregnant or breastfeeding should not consume yarrow tea, tinctures, or capsules.

What is the standard dosage for yarrow tea?

The standard adult dosage for yarrow tea is 2 to 4 grams of dried herb steeped in boiling water, taken up to three times daily. For liquid tinctures, the typical dose is 1 to 4 milliliters three times daily. Dosage may vary based on the specific condition being treated, such as fever or digestive issues.

What is yarrow used for in herbal medicine?

Yarrow is commonly used for wound healing, fever reduction, and digestive support. It is valued for its ability to stop bleeding and reduce inflammation when applied topically to cuts. Internally, it acts as a bitter tonic to aid digestion and as a diaphoretic to induce sweating during colds or fevers (Evidence Level: B).

Achillée (Achillea millefolium)

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Achillea millefolium (Yarrow) is a medicinal plant used globally for its anti-inflammatory, antioxidant, and hepatoprotective properties [PMID:19075697, PMID:42282446].

Contexte

Yarrow is a herbaceous plant in the Asteraceae family of Greek origin [PMID:38076118, PMID:35639782]. It is one of the oldest known botanicals used by humans and is significant in the pharmaceutical field [PMID:38076118].

Usages traditionnels

Historically used to treat malaria, hepatitis, jaundice, liver disorders, inflammatory and spasmodic gastro-intestinal disorders, and hepato-biliary complaints [PMID:23959026, PMID:17704978]. Other traditional indications include menstrual irregularities, cramps, fever, wound healing, cough, influenza, pneumonia, kidney stones, high blood pressure, rheumatoid arthritis, gout, osteoarthritis, hemorrhagic disorders, chicken pox, cystitis, diabetes mellitus, indigestion, dyspepsia, eczema, psoriasis, and boils [PMID:23959026, PMID:19075697].

Composés actifs

Bioactive components include flavonoids (kaempferol, luteolin, apigenin, chrysoeriol), sesquiterpene lactones (guaianolides such as millefoliumins and millefolactons), phenolic acids (caffeoylquinic acids, chlorogenic acid), polyacetylenes, simple coumarins, and monoterpenes [PMID:11558643, PMID:28868116, PMID:33761376, PMID:36963706, PMID:38869958, PMID:32722270, PMID:32325741].

Mécanisme d'action

Anti-inflammatory effects are mediated through the inhibition of nitric oxide (NO) release and repression of pro-inflammatory cytokines such as TNF-α and IL-6 [PMID:36963706, PMID:37839587, PMID:38869958]. It may modulate signaling pathways including NF-κB, PI3K/AKT/mTOR, and RAS/RAF [PMID:42282446]. Antispasmodic properties are mediated by flavonoids, while choleretic effects are caused by dicaffeoylquinic acids [PMID:17704978]. Gastroprotective actions against ethanol-induced ulcers are linked to the Nrf2/HO-1 pathway [PMID:36432009].

Preuves cliniques

Preuve CAnxiety

Showed promising effects in animal models [PMID:33480339]

Preuve DLocalized Bleeding

Hydroalcoholic extract significantly reduced bleeding time in rat liver models [PMID:38283274]

Preuve DDoxorubicin-induced renal injury

Ameliorated injury via inhibition of oxidative stress and inflammation in rats [PMID:39734352]

Preuve DCisplatin-induced ocular toxicity

Evaluated for biochemical and histopathological effects in rats [PMID:34180746]

Preuve DGastrointestinal Spasms

Hydroalcoholic extract showed antispasmodic effects in the isolated ileum of rats [PMID:24311877]

Sécurité et effets indésirables

Generally considered safe for supplemental use [PMID:23959026, PMID:28868116]. However, guinea pigs were sensitized to crude extracts of the whole plant and flowers [PMID:11558643]. Yarrow tea showed weak genotoxicity in a Drosophila melanogaster test [PMID:11558643]. In cosmetics, concerns were raised regarding components like linalool, thujone, quercetin, hydroquinone, or α-peroxyachifolid [PMID:27913788].

Interactions médicamenteuses

May interact with hormonal, antibiotic, and anticancer drugs, potentially altering concentrations of drugs such as Erythromycin, Diazepam, and Cyclosporine by affecting Cytochromes P450 metabolism enzymes [PMID:38076118].

Synthèse des preuves

The evidence is primarily based on review articles and animal/in vitro studies (Levels C and D). While traditional use is extensive and some pharmacological activities (anti-inflammatory, antioxidant) are supported by experimental data, human clinical trials are rare.

Sources PubMed

1.PMID: 33480339 (2022) — Anti-anxiety Properties of Selected Medicinal Plants. · Current pharmaceutical biotechnology
2.PMID: 38076118 (2023) — Achillea millefolium: Mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerability. · Heliyon
3.PMID: 11558643 (2001) — Final report on the safety assessment of Yarrow (Achillea millefolium) Extract. · International journal of toxicology
4.PMID: 23959026 (2013) — Minireview on Achillea millefolium Linn. · The Journal of membrane biology
5.PMID: 27913788 (2016) — Safety Assessment of Achillea millefolium as Used in Cosmetics. · International journal of toxicology

Achillée

Sources et citations

Boswellia

Turmeric

Desert Willow

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Sécurité et effets indésirables

Interactions médicamenteuses

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Achillée

Sources et citations

Plantes associées

Boswellia

Turmeric

Desert Willow

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Sécurité et effets indésirables

Interactions médicamenteuses

Synthèse des preuves

Sources PubMed

Sources gouvernementales