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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Clinopodium douglasii
A fragrant creeping mint native to western Americas, the herb that gave San Francisco's original name "Yerba Buena."
Yerba Buena (Clinopodium douglasii) is a fragrant mint traditionally used for headache, stomachache, and toothache, with modern applications as a carminative, analgesic, antimicrobial, and antispasmodic. Its key active compounds include pulegone, menthol, thymol, and carvacrol, which contribute to its therapeutic effects but also pose risks at high doses.
The analgesic and antispasmodic effects are primarily attributed to menthol, which activates TRPM8 receptors and modulates voltage-gated sodium channels, while thymol and carvacrol exhibit antimicrobial activity by disrupting bacterial cell membranes and inhibiting efflux pumps. Pulegone, a major constituent, is metabolized by CYP450 enzymes to reactive intermediates that can cause hepatotoxicity, and it also acts as a GABA-A receptor antagonist, potentially contributing to convulsant effects at high doses.
A fragrant creeping mint native to western Americas, the herb that gave San Francisco's original name "Yerba Buena."
Yerba Buena (Clinopodium douglasii) is a fragrant mint traditionally used for headache, stomachache, and toothache, with modern applications as a carminative, analgesic, antimicrobial, and antispasmodic. Its key active compounds include pulegone, menthol, thymol, and carvacrol, which contribute to its therapeutic effects but also pose risks at high doses.
The analgesic and antispasmodic effects are primarily attributed to menthol, which activates TRPM8 receptors and modulates voltage-gated sodium channels, while thymol and carvacrol exhibit antimicrobial activity by disrupting bacterial cell membranes and inhibiting efflux pumps. Pulegone, a major constituent, is metabolized by CYP450 enzymes to reactive intermediates that can cause hepatotoxicity, and it also acts as a GABA-A receptor antagonist, potentially contributing to convulsant effects at high doses.