PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extracts significantly reduced blood glucose and hyperglycemic-induced oxidative stress in diabetic rat models [PMID:14671679, PMID:27403200, PMID:16191469]
Aqueous and methanolic extracts reduced rat paw edema, though they were less potent than acetyl salicylic acid [PMID:12616962, PMID:16191469]
Aqueous corm extract significantly delayed and antagonized pentylenetetrazole- and picrotoxin-induced seizures in mice [PMID:17724761]
Aqueous extract provided dose-dependent protection against castor oil-induced diarrhea and inhibited intestinal transit in rodents [PMID:19140171]
Aqueous extract produced negative inotropic and chronotropic effects on guinea-pig atrial muscle and reduced hypertension in Dahl salt-sensitive rats [PMID:17001418]
Pregnancy & lactation
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 32527245 (2020) — African potato (Hypoxis hemerocallidea): a systematic review of its chemistry, pharmacology and ethno medicinal properties. · BMC complementary medicine and therapies
- 2.PMID: 34283859 (2021) — Transcriptome and proteome of the corm, leaf and flower of Hypoxis hemerocallidea (African potato). · PloS one
- 3.PMID: 14671679 (2003) — Hypoglycemic effect of Hypoxis hemerocallidea corm (African potato) aqueous extract in rats. · Methods and findings in experimental and clinical pharmacology
- 4.PMID: 34331304 (2022) — Benzoylcyclopropane Derivatives from Hypoxis hemerocallidea Corms. · Planta medica
- 5.PMID: 18693293 (2009) — 'African potato' (Hypoxis hemerocallidea corm): a plant-medicine for modern and 21st century diseases of mankind? - a review.