PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 24 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous extracts cause direct contractile responses in isolated rat myometrium and potentiate the initial response to oxytocin [PMID:10972206, PMID:9080339].
Ethanolic extractives of the rhizomes show antifungal activity, specifically against Trychophyton mentagrophytes and Sporothrix schenekii (MIC 15.6 microg/ml) [PMID:18343601].
Leaves of A. africanus exhibited angiotensin converting enzyme (ACE) inhibition greater than 50% [PMID:10624863].
Steroidal glycosides (including agapanthussaponin A) induce apoptosis and ferroptosis in SBC-3 human small-cell lung cancer cells via the mitochondrial pathway [PMID:36687079, PMID:40807365].
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 18343601 (2008) — Antifungal activity of Agapanthus africanus extractives. · Fitoterapia
- 2.PMID: 15907963 (2005) — Isolation and synthesis of a dimeric dihydrochalcone from Agapanthus africanus. · Phytochemistry
- 3.PMID: 27556330 (2016) — rDNA mapping, heterochromatin characterization and AT/GC content of Agapanthus africanus (L.) Hoffmanns (Agapanthaceae). · Anais da Academia Brasileira de Ciencias
- 4.PMID: 39359048 (2025) — POE-Mediated Tunable Quantum Yield of Carbon Dots-Derived From Agapanthus Africanus (L.) Hoffmann Leaves. · Small (Weinheim an der Bergstrasse, Germany)
- 5.PMID: 10972206 (2000) — The effects of herbal oxytocics on the isolated "stripped" myometrium model.