PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A phase III trial found that a regimen including Huo Xiang Zheng Qi (HXZQ) oral liquid combined with 5HT3RAs and dexamethasone significantly improved the mean number of no CINV days compared to a control group [PMID:41466018].
In vivo mouse models showed that A. rugosa relieved mucosal damage induced by HCl/EtOH [PMID:32916904, PMID:37903549].
Water and ethanol extracts improved trabecular bone loss and suppressed loss of bone strength in ovariectomized mice [PMID:32858922, PMID:33626428].
A. rugosa extract improved memory performance in scopolamine-induced mice by reducing hippocampal acetylcholinesterase activity and increasing choline acetyltransferase expression [PMID:39338335].
Essential oil inhibited the growth and acid production of Streptococcus mutans and suppressed virulence factor genes [PMID:39459275].
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 37631149 (2023) — Agastache Species: A Comprehensive Review on Phytochemical Composition and Therapeutic Properties. · Plants (Basel, Switzerland)
- 2.PMID: 36234876 (2022) — Chemical Diversity of Essential Oils from Korean Native Populations of Agastache rugosa (Korean Mint). · Molecules (Basel, Switzerland)
- 3.PMID: 41466018 (2025) — A randomized, controlled, multicenter phase III clinical trial of Huo Xiang Zheng Qi oral liquid for the prevention and control of nausea and vomiting caused by multiday cisplatin-based regimen. · Medicine
- 4.PMID: 37949898 (2023) — A chromosome-level genome assembly of Korean mint (Agastache rugosa). · Scientific data
- 5.PMID: 38974592 (2024)