PubMed-compiled information sheet
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Compiled from 1 PubMed articles · model: gemma4:31b
Summary
Aloe succotrina is a plant whose dried leaf pulp has demonstrated antihyperlipidemic activity in rat models [PMID:24693447].
Background
Aloe succotrina is a medicinal herb; studies have utilized the dried pulp of its leaves for pharmacological investigation [PMID:24693447].
Mechanism of action
The antihyperlipidemic activity of Aloe succotrina may be mediated by the inhibition of HMG-CoA reductase [PMID:24693447].
Clinical evidence
Evidence DHyperlipidemia
In Wistar albino rats, dried pulp of Aloe succotrina (200 mg/kg p.o.) significantly reversed hyperlipidemia and the atherogenic index induced by high fat diets or fructose [PMID:24693447].
Evidence summary
The current evidence is limited to a single animal study (rat model), representing a low level of clinical evidence.
PubMed sources
- 1.PMID: 24693447 (2014) — Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase. · ISRN pharmacology