PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 25 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
ACA and AEA demonstrate cytotoxic and apoptotic effects in vitro against breast (MCF-7), lung (NSCLC), cervical, and prostate cancer cells [PMID:21063268, PMID:28158287, PMID:33804975, PMID:21346553]. Cardamonin shows anticancer activity in mouse leukemia cells (WEHI-3) [PMID:31023073, PMID:31793136].
Ethanol extracts of leaves and rhizomes exhibited dose-dependent antinociceptive and anti-inflammatory activities in animal models, partially reversed by naloxone [PMID:19557202, PMID:20673172].
ACA and other isolated compounds show antimicrobial activity against Staphylococcus aureus, including MRSA [PMID:32963717, PMID:40618358].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 23266278 (2013) — Antimicrobial compounds from Alpinia conchigera. · Journal of ethnopharmacology
- 2.PMID: 32069429 (2020) — Pharmacological Effects of 1'-Acetoxychavicol Acetate, a Major Constituent in the Rhizomes of Alpinia galanga and Alpinia conchigera. · Journal of medicinal food
- 3.PMID: 32963717 (2020) — Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity. · Tropical life sciences research
- 4.PMID: 23796227 (2013) — Three unusual sesquineolignans from Alpinia conchigera. · Journal of Asian natural products research
- 5.PMID: 33466408 (2021) — Therapeutic Potential of Natural Products in Treatment of Cervical Cancer: A Review.