PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Galangin treatment alleviated cardiac myofibril damage and reduced infarction in mice models [PMID:37637264]
Galangin and DPHC demonstrate anti-proliferative effects, induce apoptosis, and arrest the cell cycle in HCC models [PMID:30551461, PMID:40058474]
Galangin reduces serum uric acid levels, inhibits UA synthesis in the liver, and promotes renal UA excretion in mice [PMID:40388492]
Included as a herbal medicine for the treatment of idiopathic male infertility in a systematic review [PMID:35993457]
Alcohol extracts significantly decreased writhing frequency and levels of PGF2α, PGE2, and Ca(2+) in the uterus of oxytocin-induced female mice [PMID:27633303]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37637264 (2023) — Galangin Attenuates Myocardial Ischemic Reperfusion-Induced Ferroptosis by Targeting Nrf2/Gpx4 Signaling Pathway. · Drug design, development and therapy
- 2.PMID: 39408345 (2024) — Potential Neuroprotective Effects of Alpinia officinarum Hance (Galangal): A Review. · Nutrients
- 3.PMID: 28969549 (2018) — Therapeutic Potential of Alpinia officinarum. · Mini reviews in medicinal chemistry
- 4.PMID: 39353308 (2024) — Insights into the anticancer effects of galangal and galangin: A comprehensive review. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 5.PMID: 39401943 (2024) — Enhanced SIRT1 Activity by Galangin Mitigates UVB-Induced Senescence in Dermal Fibroblasts via p53 Acetylation Regulation and Activation.