PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Essential oil from fruits (EOFAZ) ameliorates atherosclerosis in ApoE-/- mice and protects against aortic endothelial cell injury and inflammation [PMID:38128398, PMID:30880260]
Ethyl acetate extracts of fruits showed antihypertensive effects in L-NNA-induced hypertensive rats [PMID:37992780]
Rhizome extracts showed anti-inflammatory activity against croton oil-induced ear edema in mice [PMID:34357758]
Appears to exert anxiolytic-like effects in animal models without GABA/benzodiazepine activity [PMID:26473822]
Extracts exhibited anti-tumor activity against Ehrlich ascites carcinoma cells in vitro and in mouse xenograft models [PMID:31288458]
Proanthocyanidins (PACs) showed in vitro antiviral activity against influenza A H1N1 and porcine epidemic diarrhea virus [PMID:35124163, PMID:35087311]
Evidence summary
PubMed sources
- 1.PMID: 38930910 (2024) — Phytochemicals of Alpinia zerumbet: A Review. · Molecules (Basel, Switzerland)
- 2.PMID: 31790768 (2020) — Anti-inflammatory kavalactones from Alpinia zerumbet. · Fitoterapia
- 3.PMID: 29385084 (2018) — Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) for Human Longevity in Okinawa, Japan? · Nutrients
- 4.PMID: 26370954 (2015) — Dihydro-5,6-dehydrokavain (DDK) from Alpinia zerumbet: Its Isolation, Synthesis, and Characterization. · Molecules (Basel, Switzerland)
- 5.PMID: 38126326 (2024) — Anti-Inflammatory Terpenoids from the Rhizomes of Shell Ginger.