PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Clinical evidence
Non-polar coumarins (imperatorin and isoimperatorin) isolated from A. archangelica demonstrated significant anxiolytic-like effects in animal models at doses of 5 and 10 mg/kg [PMID:22960104]
Crude extract of A. archangelica root (CEAA) showed cytotoxicity against 4T1 and MCF-7 breast adenocarcinoma cells and protective effects against in vivo tumor development [PMID:30799248]
Optimized methanol extracts of A. archangelica roots were investigated for their role in reducing the magnitude of reserpine-induced fibromyalgia in mice [PMID:33047814]
Oral administration of A. archangelica and/or Ginkgo biloba extracts in rabbits exposed to high altitude was studied to investigate effects on hemoglobin derivatives and antioxidant enzymes [PMID:34792008]
Ethanolic extracts of A. archangelica (100 mg/kg) exhibited moderate, non-significant anticonvulsant activities in an electroshock-induced seizure model [PMID:40650201]
Evidence summary
PubMed sources
- 1.PMID: 31173794 (2019) — Wild parsnip (Pastinaca sativa)-induced photosensitization. · Toxicon : official journal of the International Society on Toxinology
- 2.PMID: 29630166 (2018) — Phytophotodermatitis induced by wild parsnip. · Dermatology online journal
- 3.PMID: 34254374 (2021) — Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components. · Phytotherapy research : PTR
- 4.PMID: 15180579 (2004) — Natural medicine: the genus Angelica. · Current medicinal chemistry
- 5.PMID: 34792008 (2022) — Angelica archangelica and Ginkgo biloba Extracts Recover Functional Blood Hemoglobin Derivatives in Rabbits Exposed to High Altitude.