Auricularia Auricula (Auricularia auricula-judae): Benefits, Dosage, Safety & Evidence

Questions fréquentes

How does Auricularia auricula work as a blood thinner?

Auricularia auricula works primarily through acidic polysaccharides and adenosine found in its fruiting body. These compounds inhibit platelet aggregation, preventing blood cells from clumping together. This antiplatelet mechanism effectively reduces blood viscosity, which supports circulation. These properties validate its traditional use in TCM for cardiovascular health, though evidence remains at Level C.

Can I take Auricularia auricula with warfarin or other blood thinners?

No, you should avoid taking Auricularia auricula if you are on anticoagulant medications like warfarin or antiplatelet drugs such as aspirin. Because this mushroom naturally inhibits platelet aggregation, combining it with pharmaceutical blood thinners can increase the risk of excessive bleeding and bruising. This interaction is clinically significant and requires medical supervision.

Is Auricularia auricula safe during pregnancy?

Auricularia auricula is considered unsafe during pregnancy due to its anticoagulant properties. The mushroom's ability to thin the blood and inhibit platelet function may increase the risk of bleeding complications during gestation and delivery. Pregnant women should avoid medicinal doses, though small culinary amounts are often viewed with caution. Consult a healthcare provider.

What is the recommended dosage for Auricularia auricula?

The standard adult dosage for Auricularia auricula is 1 to 3 grams of dried mushroom daily. This amount can be taken as a powder, decoction, or extract. In culinary contexts, it is consumed freely as food. For therapeutic cardiovascular support, sticking to the 1-3 gram range is advised to manage antiplatelet effects safely.

Does Auricularia auricula help lower cholesterol?

Traditional use suggests Auricularia auricula supports healthy cholesterol levels, likely due to its beta-glucan and fiber content which may bind to cholesterol in the gut. However, current evidence is rated Level C, indicating that while animal studies are promising, robust human clinical trials are lacking. It should not replace prescribed statin medications.

Fiche d'information compilée à partir de PubMed

Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.

Compilé à partir de 30 articles PubMed · modèle : gemma4:31b

Résumé

Auricularia auricula (also known as Auricularia auricula-judae) is a traditional edible and medicinal fungus recognized for its nutritional, pharmacological, and immunoregulatory properties [PMID:37549868, PMID:32829866].

Contexte

Auricularia auricula-judae is a saprobic European jelly fungus, often resembling a human ear, that serves as a traditional culinary and medicinal resource [PMID:38618015, PMID:33519763].

Usages traditionnels

It is a well-known traditional edible and medical fungus used in Asia for health purposes and as a traditional folk medicine for nourishing lung functions [PMID:37549868, PMID:33543932, PMID:40147652].

Composés actifs

The primary bioactive constituents are nondigestible fermentable polysaccharides (AAPs) [PMID:37549868, PMID:32829866]. Other identified components include melanin [PMID:38752125] and a specific highly branched glucuronoxylogalactoglucomannan [PMID:37230634].

Mécanisme d'action

Auricularia auricula polysaccharides (AAP) may attenuate obesity by interacting with the gut commensal Papillibacter cinnamivorans [PMID:37549868]. In models of silicosis, AAP is reported to target the epidermal growth factor receptor (EGFR) via the 'gut-lung axis' [PMID:40147652]. Additionally, AAP may regulate inflammatory responses and lipid metabolism, down-regulating liver adipogenic-related and cholesterol synthesis-related genes [PMID:35407029].

Preuves cliniques

Preuve DObesity

Dietary supplementation of AAP significantly slowed body weight gain and improved insulin resistance in high-fat diet-induced mice [PMID:37549868, PMID:35407029].

Preuve DDiabetes/Glucose Metabolism

Polysaccharide acid hydrolysates of A. auricula-judae were investigated for improving glucose metabolism in diabetic mice under oxidative stress [PMID:38640854].

Preuve DSilicosis

AAP effectively improved silicosis induced by silica (SiO2) in mice [PMID:40147652].

Preuve DCancer (TrkB-positive)

Ethyl acetate extracts of A. auricula-judae inhibited the auto-phosphorylation of tropomyosin receptor kinase B (TrkB) in vitro [PMID:36895384].

Preuve CGeneral Health

Reviews suggest beneficial effects including slowing the aging process and treating cardiovascular disorders [PMID:36677640].

Synthèse des preuves

The current evidence is primarily based on in vitro studies and animal models (mice/C. elegans), with a focus on the biological activities of polysaccharides and melanin. There are no human clinical trials provided in the source material.

Sources PubMed

1.PMID: 37549868 (2023) — Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans. · Journal of advanced research
2.PMID: 38618015 (2023) — Whose Ear?: Proposal to conserve the name Auricularia auricula (L.) Underw. for Auricularia auricula-judae (Bull.) Quél. · F1000Research
3.PMID: 36677640 (2023) — The Current State and Future Prospects of Auricularia auricula's Polysaccharide Processing Technology Portfolio. · Molecules (Basel, Switzerland)
4.PMID: 38640854 (2024) — Effects of Auricularia auricula-judae (Bull.) Quél. polysaccharide acid hydrolysate on glucose metabolism in diabetic mice under oxidative stress. · Phytomedicine : international journal of phytotherapy and phytopharmacology
5.PMID: 33543932 (2021) — Review on Auricularia auricula-judae as a Functional Food: Growth, Chemical Composition, and Biological Activities.

Auricularia Auricula

Sources et citations

Calculer une dose sûre de Auricularia Auricula

Ganoderma sinense

Allium Cepa Herb

Hu Zhang

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales

Auricularia Auricula

Sources et citations

Calculer une dose sûre de Auricularia Auricula

Plantes associées

Ganoderma sinense

Allium Cepa Herb

Hu Zhang

Questions fréquentes

Résumé

Contexte

Usages traditionnels

Composés actifs

Mécanisme d'action

Preuves cliniques

Synthèse des preuves

Sources PubMed

Sources gouvernementales