PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 26 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanol extract (400 mg/kg) significantly inhibited carrageenan-induced paw oedema and reduced cotton pellet-induced granuloma weight in animal models [PMID:16169695].
Essential oil showed anti-histaminergic and anti-cholinergic activities at 100 microg/ml in a porcine bronchial bioassay [PMID:18295421].
Ethanolic extracts demonstrated in vitro activity against enteropathogenic Escherichia coli, Salmonella enteritidis, and Shigella flexneri [PMID:8479202], as well as inhibition of Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes [PMID:20433082].
Crude ethanol extracts and fractions showed inhibitory activity against the alpha-glucosidase enzyme [PMID:36693786].
Isolated compounds including (+)-anymol, acteoside, and isoacteoside showed antiproliferative activity against murine melanoma (B16F10), human gastric adenocarcinoma (MK-1), and human uterine carcinoma (HeLa) cells [PMID:12132670].
Safety & adverse effects
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 3520154 (1986) — The intensely sweet herb, Lippia dulcis Trev.: historical uses, field inquiries, and constituents. · Journal of ethnopharmacology
- 2.PMID: 16169695 (2005) — Anti-inflammatory activity of Lippia dulcis. · Journal of ethnopharmacology
- 3.PMID: 29534573 (2018) — Key Aroma Compounds in Lippia dulcis (Dushi Button). · Journal of agricultural and food chemistry
- 4.PMID: 28655616 (2017) — Functional identification of a Lippia dulcis bornyl diphosphate synthase that contains a duplicated, inhibitory arginine-rich motif. · Biochemical and biophysical research communications
- 5.PMID: 24213688 (1991) — Lippia dulcis shoot cultures as a source of the sweet sesquiterpene hernandulcin.